Keywords: telomeres; meiosis; S. pombe; chromosome; bouquet; Cdc2-Cdc13; Rad3–Chk1; the LINC complex Cell Discovery (2017) 3, 17041; doi:10.1038/celldisc.2017.41; published online 7 November 2017 Introduction Meiosis is an essential process for the generation of genetic diversity. In early ...
During spermatogenesis, meiosis is accompanied by a robust alteration in gene expression and chromatin status. However, it remains elusive how the meiotic transcriptional program is established to ensure completion of meiotic prophase. Here, we identify a protein complex that consists of germ-cell-speci...
Remodeling of meiotic chromosomes to form an axis-loop structure is thought to be driven in part by expression of meiosis-specific cohesin subunits. All eukaryotes studied to date express one or more meiosis-specific kleisins, and some also have meiosis-specific SMC and/or Scc3/Stag isoforms10,...