PROBLEM TO BE SOLVED: To produce 3-bromo-2-(substituted phenyl)-1-propene useful as a synthetic intermediate for a pharmaceutical or agrochemical at high seleetivity and yield by using 2-phenyl-1,2,3-tribromopropane as a raw material.HOSOKAWA AKIYOSHI...
PROBLEM TO BE SOLVED: To produce 3-bromo-2-(substituted phenyl)-1-propene useful as a synthetic intermediate for a pharmaceutical or agrochemical at high seleetivity and yield by using 2-phenyl-1,2,3-tribromopropane as a raw material. ;SOLUTION: This 3-bromo-2-(substituted phenyl)-1-...
This paper presents an undergraduate computational chemistry lab experiment of the E2 elimination reaction of 2-bromopropane to form propene. Utilizing the Hartree-Fock (HF) and Density Functional Theory (DFT) methods within the computational frameworks of Avogadro and ORCA, the experiment offers a ...
When the reaction is being carried out in non-polarised media or in the presence of benzoyl peroxide, 1,1,2-trichloro-1,3-dibromopropane is obtained together with 1,1,1-trichloro-2,3-dibromopropane, the former being due to the homolytic isomerisation of the intermediate radical....