Cardiomyocytes derived from pluripotent stem cells (PSC-CMs) have been widely accepted as a promising cell source for cardiac drug screening and heart regeneration therapies. However, unlike adult cardiomyocytes, the underdeveloped structure, the immatur
The absorption and utilization of lipids are crucial for development. After the endogenous-to-exogenous nutrient source transition (eeNST) of zebrafish at 5 dpf, lipid absorption primarily occurs in the intestine, while lipid metabolism is predominantly regulated by the liver3. To further investigate ...
Cardiomyocytes derived from pluripotent stem cells (PSC-CMs) have been widely accepted as a promising cell source for cardiac drug screening and heart regeneration therapies. However, unlike adult cardiomyocytes, the underdeveloped structure, the immatur
Which hormone stimulates the release of thyroid hormones? Which hormone stimulates hemopoiesis (making blood cells)? Which hormone increases blood calcium levels? Which hormone increases calcium and phosphate ion absorption by the intestines? A) parathyroid ...
susceptibility in XX compared to XY mice is associated with enhanced absorption and bioavailability of dietary fat, which likely influences serum lipid levels and adiposity. Our findings may have important ramifications for human health, particularly following menopause, when protective effects of female ...
Moreover, PPARγ has been recognized as a crucial agent in the process of adipocyte differentiation, lipid storage, and glucose metabolism, all of which play a significant role in creating the tumor microenvironment and facilitating the survival of cancer cells [27, 28]. The abnormal lipid ...
Even when there is a large amount of oxygen in cancer cells, the reprogramming of glucose metabolism mainly involves glycolysis. Aerobic glycolysis (Warburg effect) has been shown to be the main driver of cancer [4]. Activation of the Warburg effect in cancer cells has been recognized as a ...
HCC cells with serum-free medium were placed into the upper chamber, CM of M2, OV-CRNDE-M0, and sh-CRNDE-M0 were added into the bottom plates. After incubation for 24 h, cells on the upside were erased, and the underlying ones were fixed and stained with 1% crystal violet (Sangon ...
HCC cells with serum-free medium were placed into the upper chamber, CM of M2, OV-CRNDE-M0, and sh-CRNDE-M0 were added into the bottom plates. After incubation for 24 h, cells on the upside were erased, and the underlying ones were fixed and stained with 1% crystal violet (Sangon ...
S100A8-positive cells infiltrate into the iris-ciliary body and cornea after LPS injection. No cells in the iris-ciliary body express S100A8 in the absence of LPS (Fig. 3A). S100A8-positive cells (red) were pres- ent at 18 hours (Fig. 3B), increased in number at 24–36...