A worldwide yearly survey of new data in adverse drug reactions and interactions Promethazine[SED-15, 2938; SEDA-33, 348; SEDA-34, 274] SkinAfixed drug eruptionhas been attributed topromethazine[65A]. • A 52-year-old woman with no history of allergy or skin disease took the recommended...
For decades, injectable promethazine has been associated with rare but serious limb-threatening adverse effects after extravasation or inadvertent intra-arterial injection. Patient safety organizations have called for hospitals to remove injectable promethazine from formularies, and the U.S. Food and Drug...
Avoid life-threatening adverse drug events with our Clinical API Learn more Pharmacodynamics Promethazine is is a histamine H1 antagonist that can be used for it's ability to induce sedation, reduce pain, and treat allergic reactions.12 Promethazine's effects generally last 4-6h but can last up...
Children. A possible association between phenothiazine seda- tives and sudden infant death syndrome has been suggested, but has not been confirmed (see under Adverse Effects, above). The current view in the UK and USA is that promethazine should not be given to children under 2 years of age...
(See Dosage and Administration: Administration and see Local Reactions Associated with Promethazine Hydrochloride Injection under Cautions: Adverse Effects.) If the patient complains of pain at the injection site during presumed IV injection of the drug, the injection should immediately be stopped, and ...
Anticholinergic effects of promethazine may exacerbate condition in patients with narrow-angle glaucoma or myasthenia gravis Pregnancy & Lactation Pregnancy category: C Lactation: Not known whether drug crosses into breast milk; discontinue drug, or do not nurse Pregnancy Categories A: Generally acceptable...
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. For healthcare professionals Applies to phenylephrine / promethazine:oral syrup. General adverse events One of the most commonly reported adverse reactions has included drowsiness...
Sequeira, “Evaluation of drug utilization and prescribing errors in infants: a primary care prescription-based study,” Health Policy, vol. 81, no. 2-3, pp. 350–357, 2007. M. R. Cohen, “Frequency and severity of promethazine adverse event reports obligated the ISMP alert,” Joint ...
M. R. Cohen, “Frequency and severity of promethazine adverse event reports obligated the ISMP alert,” Joint Commission Journal on Quality and Patient Safety, vol. 36, no. 3, pp. 143–144, 2010. J. Lazarou, B. H. Pomeranz, and P. N. Corey, “Incidence of adverse drug reactions in...
ADVERSE REACTIONS Central Nervous System Drowsiness is the most prominent CNS effect of this drug. Sedation, somnolence, blurred vision, dizziness; confusion, disorientation, and extrapyramidal symptoms such as oculogyric crisis, torticollis, and tongue protrusion; lassitude, tinnitus, incoordination, ...