In particular embodiments, the hydroxylase is selected from the group consisting of human HPH1, HPH2 and HPH3, and/or the substrate comprises LAPY, wherein P is hydroxylated by the hydroxylase.doi:US6566088 B1Steven L. McKnightRichard K. Bruick...
产品名称:Prolyl 4-hydroxylase subunit alpha-2 ELISA Kit 检测范围:0.78-50 ng/mL 保存条件:2-8℃低温保存 保质期:6个月,所有试剂盒均提供批次。 试剂盒成分:酶标板,试剂,标准品等。 选型: 产品规格:96T/48T 96T指可以做94个标本-2个标准对照-84个样本 ...
Prolyl 4-hydroxylase subunit alpha-1 ELISA Kit的详细说明书 检测范围:0.625-40 ng/mL 使用:本试剂仅供科研使用 保存:2-8℃ 有效期:6个月 检测方法:ELISA 产品性状:96T/48T,盒装液体 贮藏条件:2-8°C ELISA技术的优越性: (一)灵敏度高 虽然酶活性调节ELISA方法的灵敏度目前并不十分理想,但在酶活性放大EL...
we focus on prolyl 4-hydroxylase (P4H), which catalyzes the single most prevalent posttranslational modifcation in humans – the formation of (2S,4R)-4-building hydroxyproline (Hyp) (Figure 1A). Hyp was discovered in gelatin hydrolysates by Emil Fischer (Fischer, 1902; Vickery and Schmidt,...
Prolyl-4-hydroxylase 3 (PHD3) expression is downregulated during epithelial-to-mesenchymal transition. PLoS ONE. 2013;8:e83021. CentralPlace TL, Nauseef JT, Peterson MK, Henry MD, Mezhir JJ, Domann FE. Prolyl-4- Hydroxylase 3 (PHD3) Expression Is Downregulated during Epithelial-to- ...
Hypoxia inducible factor prolyl 4- hydroxylase enzymes: center stage in the battle against hypoxia, metabolic compromise and oxidative stress. Neurochem Res 2007;32(4-5):931-946.Siddiq A, Aminova LR, Ratan RR (2007) Hypoxia inducible factor prolyl 4-hydroxylase enzymes: center stage in the ...
4) Prolyl hydroxylase 脯氨酸羟化酶 例句>> 5) hydroxyproline oxidase 羟脯氨酸氧化酶 6) prolyl hydroxylase domain-containing proteins 低氧诱导因子脯氨酰羟化酶 例句>> 补充资料:脯氨酸羟化酶抑制剂 分子式: CAS号: 性质:能够抑制脯氨酸羟化酶活性的一类物质。脯氨酸羟化酶是胶原蛋白生物合成的关键酶,在...
pertension;prolyl-4-hydroxylase;placenta 【摘要】目的:通过检测脯氨酰-4-羟化酶(P4H)基因在妊 娠高血压综合征(妊高征)患者胎盘中的表达,了解其在妊高 征病理生理机制中的作用.方法:采用半定量RT-PCR技术 检测10例正常妊娠妇女(对照组)及10例中、重度妊高征患 者(妊高征组)胎盘组织P4H和!-actinmRNA水平...
Prolyl-4-hydroxylase domain 3 (PHD3) is a critical terminator for cell survival of macrophages under stress conditions. J Leukoc Biol. 2014; 96(3):... Lija,Swain,Marieke,... - 《Journal of Leukocyte Biology》 被引量: 20发表: 2014年 Hypoxia-inducible factor-1 (HIF-1) promotes its degr...
Prolyl-4-hydroxylases 专利名称:Prolyl-4-hydroxylases 发明人:RICHARD K. BRUICK,STEVEN L. MCKNIGHT 申请号:AU2002343482 申请日:20021003 公开号:AU2002343482A1 公开日:20030414 专利内容由知识产权出版社提供 摘要:The invention provides methods and compositions for assaying hypoxia-inducible factor (...