Patients are advised not to use over-the-counter PPIs for more than 4 weeks without consulting a doctor. Recent epidemiological evidence has suggested a modest increased in the risk of hip, wrist or spine fracture associated with PPI use, especial ......
Recent interest has been placed on potential pathological links between proton pump inhibitors (PPI) and the neuropathology of dementia. This study evaluates the relationship between long term use of PPIs (more than > 6 months/year and more than > 3 consecutive years) and cognitive function in ...
The role of the gut microbiome in arresting pathogen colonization and growth is important for protection against Clostridium difficile infection (CDI). Observational studies associate proton pump inhibitor (PPI) use and CDI incidence. We hypothesized that PPI use affected the distal gut microbiome over...
1. Oral Absorption of Magnesium Prolonged use of proton pump inhibitors has reportedly caused rare clinically symptomatic hypomagnesemia. A review of the literature suggests PPI drugs may... JPF Bai,E Hausman,R Lionberger,... - 《Molecular Pharmaceutics》 被引量: 70发表: 2012年 Tetany, ...
Furthermore, the present invention relates to a process for the preparation of the matrix formulation according to the invention, and the use of a matrix-forming, water-insoluble and non-swellable excipient with a water-soluble binder for the preparation of a matrix formulation having a ...
Protein–protein interaction (PPI) analysis (Fig.7E) suggested that leptin was associated with proteins encoded by circadian rhythm-related genes (Cry1,Nr1d1,Per3,Arntl/Bmal1), genes involved in inflammation and oxidative stress, angiogenesis, cell proliferation and apoptosis (Crhr2,Serpine1,A2m...
Introduction Proton pump inhibitors (PPIs) are used as prophylaxis, guarding against anastomotic stricture (AS) in the aftermath of reconstructed esophageal atresia (EA). The incidence of stricture formation was studied in this setting, comparing outcomes of 3- and 12-month PPI prophylactic regimens....
Rational PPI therapy: risks and benefits of prolonged use of proton pump inhibitors in the updated recommendations of experts of the American Gastroenterological Associationdoi:10.22141/2308-2097.51.2.2017.101704Yu.M. StepanovGastroenterologìa
S4162A Rare Case of Gastric Hyperplastic Polyps Following Prolonged PPI Usedoi:10.14309/01.ajg.0000966288.69972.9aAmanda JacubowskyLehigh Valley Health Network, Allentown, PA;Margaret SpinosaLehigh Valley Health Network, Allentown, PA;William Ghaul...
(p = 0.011), and prior thrombosis (p = 0.005) were associated with PPI use, whereas no correlations were found with respect to age, disease risk, splenomegaly, mutational status, constitutional symptoms, cardiovascular risk factors, cytoreductive treatment, or any of the blood cell counts (p ...