In this work, density functional calculations were employed to revisit the formation mechanism of enamine, the intermediate to mediate the proline-catalyzed direct aldol reaction. Different from the work of Boyd et al. [24], the plausible reaction routes were calculated on basis of the complete ...
samesideoftheC-CskeletonBasedontheknownmechanismof L・ ・ proline・ ・ catalyzedasymmetric aldol reaction,these two compoundsshouldhavethesame configuration at C-2,andhencetheabsolute configurationofthe major diastereomerof19hshould be(2R,as).Considering themechanistic similarity,inallreactions,the...
3.3. Mechanism The originally proposed mechanism of the proline-catalyzed intermolecular aldol reaction31 was based on the established class I aldolase-mechanism that involves carbinolamine, imine or iminium, and enamine intermediates.26 The catalytically active functional groups in class-I aldolases are...
Long He,Zhuo Tang,Lin-Feng Cun,Ai-Qiao Mi,Yao-Zhong Jiang,Liu-Zhu Gong.l -Proline amide-catalyzed direct asymmetric aldol reaction of aldehydes with chloroacetone[J]. Tetrahedron .2005(2)Long He,Zhou Tang,Lin-Feng Cun et al.L-Proline amide-catalyzed direct asymmetric aldol reaction of ...
Asymmetric aldol reaction catalyzed by new recyclable polystyrene-supported l-proline in the presence of water. Liu, Yu-Xia,Sun, Ya-Nan,Tan, Hao-Han,Tao, Jing-Chao. Catalysis Letters . 2008Liu Yu Xia,Sun Ya Nan,Tan Hao Han,et al.Asymmetric aldol reaction catalyzed by new recyclable ...
Yang G, Yang ZW, Zhou LJ, Zhu RX, Liu CB (2010) A revisit to proline-catalyzed aldol reaction: interactions with acetone and catalytic mechanisms. J Mol Catal A: Chem 316:112–117 Article Google Scholar Yang G, Zhu C, Zhou LJ (2015) Stabilization of zwitterionic proline by DMSO. ...
ESI-MS study on the aldol reaction catalyzed by L-prolineMarquezC.MetzgerJ. O.CHEMICAL COMMUNICATIONS- ROYAL SOCIETY OF CHEMISTRY
6. Practical asymmetric synthesis of β-hydroxy γ-amino acids via complimentary aldol reactions [O] . Bhaumik A. Pandya, Sivaraman Dandapani, Jeremy R. Duvall, -1 机译:通过互补的醛醇反应的β-羟基γ-氨基酸的实际不对称合成 7. l-Proline-Catalyzed Direct Intermolecular Asymmetric Aldol React...
ChemInform Abstract: Asymmetric Aldol Reaction Catalyzed by the Self‐Assembled Nanostructures of L‐Proline Containing Amphiphilic Dipeptide: A Morphological Dependence.alcohols (benzene compounds)diastereoselective syntheses, enantioselective syntheses (incl. cis/trans‐isomerism)...
1) L-proline-catalyzed aldol reaction L-脯氨酸催化的羟醛缩合反应2) Cu(C 5H 8NO 3) 2 L-羟脯氨酸合铜3) L-hydroxyproline L-羟脯氨酸 1. Coordination Mechanism and Antioxidant Activity of L-hydroxyproline Zinc(Ⅱ); L-羟脯氨酸-Zn(Ⅱ)的配合机制及其抗氧化性研究 2. Determination of...