Prokinetics is expected to be effective as a long-term treatment. It is essential to make progress with development of new drugs, including prokinetics, as well as application of existing drugs.Functional Dyspepsiadoi:10.1007/978-981-13-1074-4_12Toshihisa Takeuchi...
Prokinetic agents have been widely employed in pediatric patients in order to reduce the symptoms of GERD. These drugs seem to enhance lower esophageal sphincter (LES) tone, to improve esophageal clearance, and to increase gastric motility thus increasing emptying of gastric contents. Cisapride was ...
drugs that increase urine production and increase H2O and Na excretion, alter solute reabsorption at the nephron (increased tubular H2O/U+ volume, decreased ECF) mannitol osmotic diuretic, filtered at glomerulus and poorly reabsorbed from the lumen of the nephron, attract water to luminal side of...
cilansetron), regulatory agencies have raised the bar significantly when it comes to the approval of prokinetic and related drugs. On the assumption that t... EMM Quigley - 《Current Gastroenterology Reports》 被引量: 0发表: 2017年 Gastrointestinal motor disorders: treatment with prokinetics Proki...
The importance of prokinetics (drugs stimulating motor function of the gastrointestinal tract) arises from the high prevalence of gastroenterological pathology associated with primary or secondary disturbances of this function in esophagus, stomach, and intestines. The main groups of prokinetics are beta-...
et al. Use of acid-suppressive drugs and risk of pneumonia: a systematic review and meta-analysis. Canadian Medical Association Journal. 183, 310–9 (2011). Article PubMed PubMed Central Google Scholar Lam, J. R., Schneider, J. L., Zhao, W. & Corley, D. A. Proton pump inhibitor...
W. Translating old drugs into new treatments: ribosomal frameshifting as a target for antiviral agents. Trends Biotechnol 16, 190–196 (1998). 8. Kim, Y. C., Su, L., Maas, S., O'Neill, A. & Rich, A. Specific mutations in a viral RNA pseudoknot drastically change ribosomal ...
Drugs that act on the gastrointestinal tract may be categorized into three groups: (1) agents that enhance smooth muscle contractions, referred to as prokinetic agents; (2) agents that inhibit contractions, which may be agents that retard normal peristalsis referred to as antimotility agents (...
Prokinetic agents have been widely employed in pediatric patients in order to reduce the symptoms of GERD. These drugs seem to enhance lower esophageal sphincter (LES) tone, to improve esophageal clearance, and to increase gastric motility thus increasing emptying of gastric contents. Cisapride was ...
The primary comparisons will be as follows. Are prokinetic drugs in general better than placebo? Which of the individual prokinetic drugs is the most effective?doi:10.1002/14651858.CD009431Natasha P BollegalaReena KhannaPaul MoayyediGrigorios I LeontiadisJohn Wiley & Sons, Ltd...