Germ-free animals, induced for EAE, produce lower levels of the proinflammatory cytokines IFN-纬 and IL-17A in both the intestine and spinal cord but display a reciprocal increase in ...
Tc17 cells are a proinflammatory, plastic lineage of pathogenic CD8(+) T cells that induce GVHD without antileukemic effects Kuns, et al., Tc17 cells are a proinflammatory, plastic lineage of pathogenic CD8+ T cells that induce GVHD without antileukemic effects, Blood 126 (... McCluskey,Ja...
Proinflammatory Responses and Higher IL-10 Production by T Cells Correlate with Protection against Malaria during Pregnancy and Delivery Outcomes Proinflammatory responses and higher IL-10 production by T cells correlate with protection against malaria during pregnancy and delivery outcomes. J Immunol ......
Objective To explore the proportion of TCR γδT(γδT) cells and the cytokine production ability of the γδT cells in peripheral blood of patients with hepatitis B virus-associated acute-on-chronic liver failure(HBV-ACLF),and to analyze the correlation between the proportion of cells and th...
In addition, Cal/BDP significantly suppressed the interleukin (IL)-23/IL-17-producing T (T17) pathogenic axis, including expression of,,andmRNA in skin lesions and expansion of CCR6γδ T17 cells in the draining lymph nodes. Notably, Cal/BDP synergistically induced regulatory CD8T cells and...
interaction, suppressing necroptosis [39]. It has recently been shown that mice deficient in Caspase-8 and RIPK3 mount elevated levels of CD8 T cells in response to MCMV infection, suggesting the cell death-independent role of Caspase-8 during restricting antiviral CD8 T cell hyperaccumulation [...
Magnetically sorted CD4+,CD25– and CD4+,CD25+ T cells derived from the PB and SF obtained from RA patients were stimulated alone or in coculture with anti-CD3 monoclonal antibody (mAb) and autologous antigen-presenting cells, in the absence or presence of anti-CD28 mAb or the ...
This is a review concerning the role of interleukin-17, a proinflammatory cytokine, produced by activated + T cells, in of . As interleukin-17 shares properties with IL-1 and , it may induce and bone and cartilage destruction. This cytokine is found in synovial fluids of patients with , ...
Su.47. The Proinflammatory Action of Cd4+Cd25 T-Cells in Murine Endotoxemia Is Controlled By Naturally Occurring Cd4+Cd25+ Regulatory T-Cells... VD Wilde,F Benghiat,M Novalrivas,... - 《Clinical Immunology》 被引量: 0发表: 2006年 TSG-14 transgenic mice have improved survival to endotoxemi...
Direct influences of pro-inflammatory cytokines (IL-1beta, TNF-alpha, IL-6) on the proliferation and cell-surface antigen expression of cancer cells. Cytokine 2000; 12: 8-11.Kuninaka S,Yano T,Yokoyama H,et al.Direct influences of pro-inflammatory cytokines (IL-1beta, TNF-alpha, IL-6) ...