Any chronic or dread disease (e.g., cancer), which progresses with time in scope and/or severity.OncologyA term defined in the context of clinical trials as tumour growth of ≥ 20% since treatment began, including local or metastatic tumour mass. Segen's Medical Dictionary. © 2012 ...
Dyspnea is one of the most common symptoms in the clinical setting, the main causes being represented by respiratory and cardiovascular disorders but sometimes it is difficult to identify and document the underlying mechanism of breathlessness. We present the case of a 75-years-old male patient, ...
Effects of lung resection on pulmonary function and exercise capacity. The effects of lung resection on exercise capacity and perception of symptoms were studied in 47 patients aged 39-73 (mean 58.3) years. Twenty had a pneumo... C Pelletier,L Lapointe,P Leblanc - 《Thorax》 被引量: 249发...
A right-to-left shunt is more likely to appear after a right-sided lung resection with most patients having symptoms develop a month to several months afterwards. Noncardiac causes can include intrapulmonary shunting, such as thromboembolic disease and AVMs, or cirrhosis and kyphoscolisoss. The ...
(control,n = 9 mice; conditionalNedd4-2−/−,n = 6 mice) of doxycycline induction.e–gMicro-CT imaging studies were performed after an average of 4 month of doxycycline induction when conditionalNedd4-2−/−mice developed clinical symptoms (n = 7/group).eRepresentative...
20% of patients were accompanied by tumors, including thymoma, Hodgkin’s lymphoma, lung cancer, renal cell carcinoma, etc. Notably, symptoms related to tumors, such as those associated with thymoma, show substantial improvement following tumor resection [23]. Additionally, cases of Hodgkin’s ...
20% of patients were accompanied by tumors, including thymoma, Hodgkin’s lymphoma, lung cancer, renal cell carcinoma, etc. Notably, symptoms related to tumors, such as those associated with thymoma, show substantial improvement following tumor resection [23]. Additionally, cases of Hodgkin’s ...
Traditionally, metastatic disease has been regarded as incurable and the role of local therapy has been limited to palliation of symptoms.8 Because of our evolving understanding of cancer biology and improvement in systemic therapy, it is now recognized that the spectrum of metastatic disease differs...
(alveolar proteinosis). When PMF occurs, clinical symptoms characteristic of restrictive lung disease develop, such as decrease in total lung capacity and lung compliance, and are associated with dyspnea. Like the tissue response, the effects on lung function are progressive, and death associated ...
Regarding safety, diarrhea and flushing symptoms incidence did not worsen over time, and no deterioration of QoL was reported in either the pancreatic or the midgut NETs cohorts. For example, the mean (SD) change from baseline to end of study/early withdrawal in EQ-5...