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The definition of the activation is somehow arbitrary: one could think, for instance, to change the threshold t or the number of inactive years. We find however our choice to be a good trade-off to have both a good numerosity of the test set and avoid the influence of trivial 0/1 ...
28 Principle coordinate analysis (PCoA) is the modified version of PCA analysis, in which different distance metrics (e.g., Bray-Curtis distances) can be used, compared to the Euclidean distances that is solely used in PCA. Both PCA and PCoA analysis used in this study were performed at ...
an orthogonal partial least squares discriminant analysis (OPLS-DA) was established. The control group and liver fibrosis model group could be separated completely at all time points (weeks 2, 4, 6, and 8) in the OPLS-DA score plots (Supplementary Fig.S2A–D). The parameters...
The brethren direct me to say that the Church has never announced a definite doctrine upon this point. Some of the brethren have held the view that it was possible in the course of progression to advance from one glory to another, invoking the principle
Prior work has suggested that as tumors progress, the level of spatial heterogeneity decreases while molecular heterogeneity increases [49], in principle, because tumor regions outcompete other cell types and outgrowth precludes the existence of more (visually) complex secondary structures. This conclusion...