Academic literature on Indias economic history often portrays the nations Green Revolution as a single package of technocratic reforms that eventually led to sustained growth in Indias total agricultural production the quintessential triumph of science over political resistance. This account, though, is a...
Mutations or altered expression of splicing factors can lead to splicing reprogramming, which contributes to tumor initiation and progression. For example, SF3B1 mutations induce mis-splicing ofBRD9, leading to its degradation and the promotion of melanomagenesis12. U2AF1 mutations cause abnormal recog...
Apple Academic Press, Oakville, CA, p 104 Mekonnen MM, Hoekstra AY (2010) A global and high-resolution assessment of the green, blue and grey water footprint of wheat. Hydrol Earth Syst Sci 14:1259–1276. https://doi.org/10.5194/ hess-14-1259-2010 Me...
Increasing lines of evidence indicate the role of long non-coding RNAs (LncRNAs) in gene regulation and tumor development. Hence, it is important to elucidate the mechanisms of LncRNAs underlying the proliferation, metastasis, and invasion of lung adenoc
Lung cancer poses a serious threat to human health, but its molecular mechanisms remain unclear. Circular RNAs (circRNAs) are closely associated with tumour progression, and the important role of 8-oxoguanine (o8G) modification in regulating the fate of
Acute promyelocytic leukemia (APL) is driven by the oncoprotein PML-RARα, which antagonizes myeloid differentiation and promotes APL-initiating cell self-renewal. Combined all-trans retinoic acid (ATRA) with arsenic trioxide (As2O3) or chemotherapy dramatically improves the prognosis of APL patients....
Our clustering algorithm categorized the regions into inner, middle, and edge regions. In the illustration, the red area on the left corresponds to the middle region, while the green area on the right corresponds to the middle region. c OR of clinical features in univariable analysis, d OR ...
(ICB) and T-cell therapy have made significant breakthroughs in improving the clinical prognosis of several types of solid tumors (13,14), demonstrating an effective response to immunotherapy for tumors. Literature (15,16) has revealed several biomarkers associated with immunity and prognosis, but ...
Our clustering algorithm categorized the regions into inner, middle, and edge regions. In the illustration, the red area on the left corresponds to the middle region, while the green area on the right corresponds to the middle region. c OR of clinical features in univariable analysis, d OR ...
Different molecular mechanisms account for the development of endocrine resistance, which mainly revolve around ER function. In fact, ER expression is absent or low in breast CSCs [7]. In addition to the loss of ER, other mechanisms are the acquisition of gain-of-function mutations in ESR1 [...