The study also builds on previous research which has found that infections can sometimes trigger a relapse or temporary worsening of symptoms in MS. This new study suggests that inflammation, which can be caused by infections like colds, flu and UTIs (urinary tract infections), is linked with t...
Multiple sclerosis(MS) is an immune-mediated inflammatory disease that attacks myelinated axons in the central nervous system (CNS) and often causes significant physical disability over time. Thehallmarkof MS is symptomatic episodes "separated in time and space," which are heralded by symptoms that...
The therapy was found to significantly lower the risk of first and confirmed (three-month) disability progression, and to reduce the risk of becoming wheelchair-bound in a broad population of progressive MS patients, compared with a placebo. “These ...
A group of 891 patients was assessed over time to evaluate the rate of conversion from relapsing-remitting MS to secondary progressive MS (steady decline that develops after a period of relapsing-remitting symptoms). During an average of 3.34 years, 72 patients (20 of 154 smokers, 20 of 237 ...
Glial fibrillary acidic protein (GFAP), an intracellular type III intermediate filament protein, provides structural support and maintains the mechanical integrity of astrocytes. It is predominantly found in the astrocytes which are the most abundant sub
Conclusion: Men and patients who presented at age 40 yeas or beyond had increased risk of MS progression. Spinal cord symptoms at onset and 3 or more relapses were predictive of progression.R. A. AlroughaniDivision of NeurologyS. Akhtar...
Moreover, half of the ONFH hips had already collapsed at the initial diagnosis, and 63% of the cases were bilateral [3]. Another study reported that 59% of untreated ONFH cases progressed to symptoms or collapse [4]. Most ONFH cases eventually progress to secondary osteoarthritis (OA), ...
“The most important take-home point of this study is we, as physicians and hematologists, can initiate the smoking cessation counseling in patients who are first diagnosed with myelodysplastic syndrome,” Sangeetha Venugopal, MD, MS, a physician in the Department of Medicine, Division of...
By current definition, people with benign MS are those who remain "fully functional" after 15 or more years from disease onset. However, people with benign MS occasionally develop renewed disease activity or progression, and can experience severe symptoms. ...
Patients were also stratified into five clinical forms based on first disease-related symptoms onset: (I) congenital (at birth), (II) infantile (1–10 years), (III) juvenile (11–20 years), (IV) adult (21–40 years) and (V) late onset (> 40 years). All patients received a comp...