Background: Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) are an effective treatment for non-small-cell lung cancer (NSCLC) harbouring EGFR mutations. The development of isolated central nervous sy...
Lung cancer is the leading cause of cancer-related death worldwide. Glypican-5 (GPC5) is a member of heparan sulfate proteoglycans, and its biological importance in initiation and progression of lung cancer remains controversial. In the present study, we revealed that GPC5 transcriptionally enhanced...
A. C-Raf is required for the initiation of lung cancer by K-Ras(G12D). Cancer Discov. 1, 128–136 (2011). Article CAS PubMed PubMed Central Google Scholar Venkatanarayan, A. et al. CRAF dimerization with ARAF regulates KRAS-driven tumor growth. Cell Rep. 38, 110351 (2022). This...
Treatment Options for Advanced RAI-R-DTC After Progression on Lenvatinib EP: 5.Investigational Agents and Ongoing Clinical Trials in Advanced RAI-R-DTC EP: 6.An Overview of Advanced Radioactive Iodine-Refractory Differentiated Thyroid Cancer (RAI-R-DTC)...
EP: 14.Future Directions in Treatment of Small Cell Lung Cancer Hossein Borghaei, DO, MS: We’re going to move on to the second segment of the study, which has to do with relapsed/refractory small cell lung cancer. We’re going to discuss some treatment options for patients who have ...
craig2097over a year ago Hi, I must say that it is a pity she didn’t notice it before, while she could prevent spreading of the cancer by therapy or even if necessary removing the infected to prevent any new malignant occurrence. The metastatic activity of a tumor, increases with both ...
(durvalumab) demonstrated a statistically significant and clinically meaningful improvement in the dual primary endpoints of overall survival (OS) and progression-free survival (PFS) in patients with limited-stage small cell lung cancer (LS-SCLC) who had not progressed following concurrent ...
Non-Small Cell Lung Cancer (NSCLC) |Treatment Algorithms with the Oncology Brothers |Treatment Algorithm for Metastatic Non–Small Cell Lung Cancer (NSCLC) Precision Medicine in NSCLC The Power of Molecular Testing Charu Aggarwal, MD, MPH;Christine Bestvina, MD;Hatim Husain, MD;Karen L. Reck...
2.4. Cell culture and treatment The human endometrial cancer cell lines Ishikawa was kindly provided by the cell bank of the Chinese Academy of Science (Shanghai, China). All cell lines were authenticated by the provider based on morphology, antigen expression, growth, DNA profile, and cytogenet...
Significantly high-expressed circFLNA has been found in various cancer cell lines, but not in lung cancer. Therefore, this study aimed to explore the role of circFLNA in the progression of lung cancer. The target gene of circFLNA was determined by bioinf