European Journal of Medicinal Chemistry Supports open access 11.7CiteScore 6.0Impact Factor Articles & Issues About Publish Order journal Submit your articleGuide for authors Volume 281 In progress (5 January 2025) This issue is in progress but contains articles that are final and fully citable. ...
Direct targeting of hypoxia-related molecules such as hypoxia-inducible factor-1alpha, the central regulator of the hypoxic response in tumor cells, is an... Bache,Kappler,H M,... - 《Current Medicinal Chemistry》 被引量: 119发表: 2008年 Gene Expression Profiles of Epidermal Growth Factor Rec...
However, the research method of serum medicinal chemistry has its shortcomings. Firstly, it is not suitable for stimulating the gastrointestinal tract and other drugs that do not pass through the blood. On the other hand, in the process of serum preparation and inactivation, it may lead to the...
In future research, interdisciplinary collaboration between NP chemistry, medicinal chemistry, pharmacology, chemical biology, and other related fields should be emphasized to enhance the success rate of new drug discovery based on NPs. For instance, chemical biology can be employed to harness the ...
The morbidity and mortality rates associated with vascular disease (VD) have been gradually increasing. Currently, the most common treatment for VD is surgery, with the progress in drug therapy remaining slow. Cannabidiol (CBD) is a natural extract of Ca
in Annual Reports in Medicinal Chemistry Vol. 36 (ed. Doherty, A.M.) 293–318 (Academic Press, San Diego, USA, 2001). 125 Clardy, J., Fischbach, M. A. & Walsh, C. T. New antibiotics from bacterial natural products. Nat. Biotechnol. 24, 1541–1550 (2006). The Journal of ...
The laureates' work enables numerous avenues for molecular scientists, from CH activation chemistry to PROTAC technology, medicinal chemistry, and epigenetics. The Nobel Prize in Medicine or Physiology 2019 was awarded for discoveries of how cells sense and adapt to oxygen availability. This Highlight...
Significant research has been conducted in this field as synthesizing these materials now requires careful consideration of green chemistry principles, minimization of disposal, cleaner solvents, energy efficiency, and caring precursor ingredients. The goal of this work is to evaluate the characteristics ...
HIV Protease Inhibition: Limited Recent Progress and Advances in Understanding Current Pitfalls, Antiviral Profile of HIV Inhibitors in Macrophages: Implications ... P Idoi - 《Current Topics in Medicinal Chemistry》 被引量: 0发表: 0年 Clinical Pharmacokinetics of Diclofenac Diclofenac is a nonsteroida...
COVID-19 has been a major global health concern for the past three years, and currently we are still experiencing coronavirus patients in the following years. The virus, known as SARS-CoV-2, shares a similar genomic identity with previous viruses such as