程序性细胞死亡又称为细胞凋亡(apoptosis),是指为维持内环境稳定,由基因控制的细胞自主的有序性的死亡,它涉及一系列基因的激活、表达以及调控等的作用,因而是具有生理性和选择性的。 Apoptosis的概念来自于希腊语,原意是指树叶或花的自然凋落,而细胞发生程序性死亡时,就像树叶或花的自然凋落一样,凋亡的细胞散在于正...
ApoptosisX-Linked Inhibitor of Apoptosis ProteinAutophagyThis year's Cold Spring Harbor meeting on programmed cell death (September 17-21, 2003), organised by Craig Thompson and Junying Yuan, was proof that the 'golden age' of research in this field is far from over. There was a flurry of ...
protein activation cascades and modulation of gene expression. Although programmed cell death has been usually identified as a synonymous of apoptosis, it also includes different caspase-independent death programs such as autophagy,paraptosis,necroptosisormitotic catastrophe(Broker et al., 2005; de Brui...
Clear cell renal cell carcinoma (ccRCC) is one of the most common renal malignancies of the urinary system. Patient outcomes are relatively poor due to the lack of early diagnostic markers and resistance to existing treatment options. Programmed cell death, also known as apoptosis, is a highly ...
程序性细胞死亡(programmed cell death)是细胞在基因调控下主动、有序地结束生命的过程,在生物发育、组织稳态及疾病中具有
Programmed cell death pathways in cancer: a review of apoptosis, autophagy and programmed necrosis. Cell Prolif 2012;45:487-98.Ouyang L, Shi Z, Zhao S, Wang FT, Zhou TT, Liu B, et al. Programmed cell death pathways in cancer: a review of apoptosis, autophagy and programmed necro- sis...
Salmonella-induced cell death: apoptosis, necrosis or programmed cell death? Trends Microbiol 9: 64-67.Boise, L. H., and Collins, C. M. (2001) Salmonella-induced cell death: apoptosis, necrosis or programmed cell death? Trends Microbiol. 9(2): 64-67....
【医学界】程序性细胞死亡(Programmed Cell Death, PCD)是生命体在漫长进化过程中产生的细胞自杀机制,包括细胞凋亡(Apoptosis)、坏死性凋亡(Necroptosis)、细胞焦亡(Pyroptosis)、自噬(Autophagy)、铁死亡(Ferroptosis)以及铜死亡(Cuproptosis)等,本文汇总以上细胞死亡方式的原理以及检测的关键靶标,帮助小伙伴们轻松开启科研...
细胞凋亡 (apoptosis)也称为细胞程序性死亡 (programmedcelldeath ,PCD) ,是由细胞自身的程序性自杀机制激活的细胞死亡现象。在多细胞真核生物中 ,程序性的细胞死亡是由细胞表面的死亡受体介导 ,通过一系列的半胱氨酸蛋白酶 (caspases)作用而启动1] ,维系个体结构稳定、功能平衡和生长发育所必需的基本生物学过程。
Programmed cell death (PCD) is an active and gene_regulated process which plays an important role in normal growth and development of plants. 细胞程序化死亡 (PCD)是一种由基因控制的、主动的细胞死亡过程 ,它在植物正常生长发育过程中起着重要作用。 2. Fumonisin B1 (FB_1)induces programmed cell ...