While some studies have reported a poor prognosis for locoregional recurrence (LRR) following breast cancer surgery, the prognosis of LRR without simultaneous distant metastasis after IBR is not known. We conducted a multi-facility retrospective observational study to investigate the prognosis of breast ...
The aim of the work described in this paper is to investigate whether frequent pattern mining methods, especially our SFM(Swarm to Frequent Nodesets Mining), are able to give prediction of recurrence in medical applications. The results provide evidence that our approach (1) can be very efficien...
Recently, we and others have demonstrated that transcriptomic data can be leveraged to dissect the tumor microenvironment14,15,16,17,18,19. Such methods have shown that elevated expression of leukocyte marker genes associates with a lower risk of breast cancer recurrence14,17,20,21. Notably, Ali...
we found that breast cancer patients with type-2 DM had a worse prognosis compared with those without type-2 DM in subgroup populations with involved lymph nodes or with any status of ER.It was interesting that in breast cancer patients who had received chemotherapy,the risk of recurrence or ...
Long non-coding RNAs (lncRNAs) involved in metabolism are recognized as significant factors in breast cancer (BC) progression. We constructed a novel prognostic signature for BC using metabolism-related lncRNAs and investigated their underlying mechanism
Cancer is an aggressive disease with a low median survival rate. Ironically, the treatment process is long and very costly due to its high recurrence and mortality rates. Accurate early diagnosis and prognosis prediction of cancer are essential to enhance the patient's survival rate. Developments ...
By predicting the risk of recurrence in patients with breast cancer, high-risk cancer patients can benefit from adjuvant therapy, while low-risk cancer patients can be protected from unnecessary treatment. The microarray data of ER+ breast cancer and ER breast cancer were analyzed in this paper....
Tumor microenvironment immunity is associated with breast cancer outcome. A high lymphocytic infiltration has been associated with response to neoadjuvant chemotherapy, but the contribution to response and prognosis of immune cell subpopulations profiles
1.A method for detecting the methylation status in a human subject who is in a need of detection of a breast cancer or detecting a predisposition to, or the incidence of, a breast cancer or predicting treatment response, prognosis or recurrence of a breast cancer in a human subject, where...
Physical activity, risk of death and recurrence in breast cancer survivors: A systematic review and meta-analysis of epidemiological studies Strong evidence exists supporting the effect of lack of physical activity on the risk of developing breast cancer. However, studies examining the effects of physi...