It has been applied as a standard tool for assessing the prognosis of patients with various cancer types, but its accuracy in individual survival prediction still needs to be improved. For example, a deep learning survival prediction model established for stage III NSCLC showed better prognostic ...
Gene expression profiles for colorectal cancer (CRC) cohorts were obtained from The Cancer Genome Atlas (TCGA) portal, accessible at https://portal.gdc.cancer.gov/. We accessed raw read counts and associated clinical information including age, gender, cancer stage, overall survival (OS), and ...
High-risk group based on the signature comprises more high-grade (G3AndG4) and advanced pathologic stage (stageIII/IV) tumors and presents hyperactivation of cell cycle process according to the functional analysis. Meanwhile, high-risk tumors demonstrate an immunosuppressive phenotype with more ...
women showed a significantly higher incidence of the primary endpoint after multivariable Cox regression analysis, which was adjusted for age, CCI, income, and clinical variables including dyslipidemia, IHD requiring coronary intervention, chronic kidney disease,...
According to the FIGO classification system, 4 patients were allocated to Stage I, 2 were Stage II, 13 were Stage III, and 3 were Stage IV. The 5-year actuarial survival rate for all patients was 76%. Conservative treatment in addition to retrieval therapy upon recurrence could achieve 100...
Based on the results, the risk score, T stage, and N stage were included in the nomogram (Fig. 6a). The C-index of the nomogram was 0.83, suggesting favorable discrimination ability. The ROC curves were plotted for 3-year and 5-year survival, and the respective area under the curve (...
and KPS. Model 3 was adjusted for age, sex, BMI, TNM stage, KPS score, tumour type, surgery, radiotherapy, chemotherapy, hypertension, diabetes, smoking, drinking, family history, and PG-SGA. Additionally, we conducted subgroup analyses and tested the associations among EN, IBI, and cancer ...
The authors noted that the AUC to identify a clinically significant PCa was 0.698 for the PHI, while it was only 0.654 for %fPSA. Also, Fossati et al. [18] indicated that both the PHI and %[−2]proPSA predicted a pathologic stage T3 and a Gleason score ≥7 in the surgical ...
González-Pacheco M, Prior-Sánchez I, Carmona-Llanos A, Muñoz-Jiménez C, et al. Ultrasound Muscle Evaluation for Predicting the Prognosis of Patients with Head and Neck Cancer: A Large-Scale and Multicenter Prospective Study.Nutrients. 2024; 16(3):387. https://doi.org/10.3390/nu16030387...
unfortunately, mesothelioma is fatal for many patients. in part, this is because it is a rare cancer that may be discovered at a later stage of disease progression. mesothelioma may also be misdiagnosed as other forms of cancer. another factor is that there is currently no cure for ...