Despite marked recent advances in chemotherapy, few reports have focused on the prognosis for patients with metastatic colorectal cancer (mCRC) achieving complete response (CR) after systemic chemotherapy. This study investigated the clinical course of mCRC patients achieving CR and evaluated the role ...
RESULTS: Few patients with metastatic cancers (16.5%) reported an accurate awareness of their prognosis, defined as reporting a life expectancy of less than 2 years for lung cancer or less than 5 years for colorectal cancer. Patients whose most-important-doctor (in helping patient make decisions...
reported that the incidence of localized prostate cancer declined across age groups from 2012 to 2015, however, the incidence of distant metastatic disease increased gradually17. These metastases are associated with poor prognosis, bone pain, and pathological characteristics and indicate the incurability ...
Metastatic prostate cancer (mPCa) rarely occurs under the age of 60, and we aim to evaluate the clinical outcomes and prognosis of mPCa patients≤60-year-old.Two thousand and eighty-three patients were treated with mPCa between April 2003 and May 2020. Clinicopathological characteristics between gr...
For more advanced cancers, functional status has consistently demonstrated an association with survival, although length of survival may depend on the underlying cancer. For example, for patients with metastatic cancer with relatively good treatment options, such as prostate or breast cancer, prognosis ...
They applied this workflow to create a comprehensive dataset of pan-cancer tumor microbial abundances derived from WGS or RNA-seq data for the entire TCGA cohort. Our central research questions then were, (1) does a data-driven ML approach reveal that tumor microbial abundances in TCGA data, ...
However, the prognosis remains poor for frail, elderly patients with an impaired performance status. 1. Introduction Approximately 20–30% of renal cell cancer (RCC) patients have distant metastases at the time of initial diagnosis [1], thus being diagnosed with synchronous metastatic renal cell ...
From 1979 to 1982, 163 patients with colorectal cancer were found to have distant metastases. Of these, 112 (69%) had metastatic disease at the time of initial diagnosis (synchronous metastases [SM]); in the remaining 51 (31%) metastases developed during the course of the disease (metachrono...
Luminal B subtype as a predictive biomarker of docetaxel benefit for newly diagnosed metastatic hormone sensitive prostate cancer (mHSPC): a correlative study of E3805 CHAARTED. Presented at: ASCO Annual Meeting; 2019; Chicago, IL. 14. Cerami E, Gao J, Dogrusoz U, et al. The ...
Cell-free circulating tumor DNA (ctDNA) in plasma has been used as a potential noninvasive biomarker for various tumors. The current study was performed to evaluate the clinical implications of ctDNA detection in patients with metastatic pancreatic cancer. Firstly, we attempted to prospectively scree...