later analysis demonstrated that the risk difference in the E/P arm was based on a lower BC risk in women with any prior hormone use [66]. In contrast, from the very beginning, the E-only arm of the WHI showed protection against BC [67], exactly what ...
later analysis demonstrated that the risk difference in the E/P arm was based on a lower BC risk in women with any prior hormone use [66]. In contrast, from the very beginning, the E-only arm of the WHI showed protection against BC [67], exactly what ...
In the general population, the clinical pregnancy rate was significantly higher after blastocyst transfer (33.3%) than after cleaved embryo transfer (25.3%; p < 0.01); the same was true for the birth rate (32.1 and 22.8%, respectively, p < 0.01). The differences between blastocys...
In this mouse line, the conditional Pgrmc1/2 knockout mice ovulated and became pregnant but the birth of pups was rarely observed after 6 months of age compare to controls whose fertility was not affected at 6 months of age. The major cause of the reproductive wastage was associated with ...
We also examined whether cyclic AMP (cAMP), a vital messenger molecule that controls oogenesis, was involved in this process. Results P4–BSA inhibited primordial follicle formation. To determine whether membrane P4 receptor or nPRs mediated the effect of P4 on primordial follicle formation, we...
Gonadotropin dosage was adjusted based on monitoring the follicular size using transvaginal ultrasound (Acuson 128-P-10; Acuson, Mountain View, CA) after gonadotropin administration for 6 days. Human chorionic gonadotropin, 10,000 IU IM (Profasi; Serono), was given to trigger ovulation when two ...
In autoimmune diseases, pregnant systemic lupus erythematosus (SLE) patients were found to have reduced levels of progesterone and higher incidence of preterm birth when compared with healthy pregnant controls11. In addition, progesterone inhibits toll-like receptors (TLRs)-mediated activation of ...
It sustains decidualization [7], controls uterine contractility and promotes maternal immune tolerance to the fetal semi-allograft [8]. Lymphocytes, in the presence of progesterone, also release progesterone-induced blocking factor (PIBF). PIBF is a pivotal mediator in progesterone-dependent ...
3C). Based on the RNA-seq results, we determined the expression of glycolysis and fatty acid synthesis pathway (P < 0.05, 2-fold change; Fig. 3D). We observed the upregulation of target genes with important roles in lipogenesis and fatty acid synthesis among the transcription factors ...
Negative controls were performed by omitting primary antibodies. Statistical analysis The number of patients with positive of estrogen or progesterone receptors was presented as a percentage with lower and upper confidence limits (95%CI), which express the lower and upper ends of the interval. The ...