Overactive bladder (OAB) presents a high prevalence of 16–18% worldwide. The pathophysiology of OAB is still poorly understood while effective therapy or countermeasure are very limited. On the other hand, med
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Through past several years, a number of JAK mutations that lead to activation of constitutively active or hyperactive JAK activity have been identified [64]. The genetic alteration of JAK family has been reported in all members. It is a well known fact that JAK mutations is linked with develop...
Silibinin (Figure 1D), a mixture of flavonoids derived from Silybum marianum (Shuifeiji), is therapeutically used for the treatment of hepatic diseases in China, Germany and Japan. Silibinin has effects on many cancers, such as prostate, colon, bladder and lung cancers [55, 56], particularly ...
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