Hard-to-produce ProteinsOver the past decades, the CHO cell has become increasingly popular as the favorite host cell line for the production of protein based therapeutic drugs. In comparison with the popularity of the CHO cells and the frequent use of these cells to produce a la...
The membrane proteins that serve to transmit signals from the outside of the cell to the inside of the cell are called: A. transporters. B. structural proteins. C. recognition proteins. D. enzymes. E. receptors. What are the various types of membrane ...
We are using this understanding to engineer new CHO cell lines having significantly improved features for the production of therapeutic proteins. We are not only doing this by improving the titer, quality, downstream processing and speed of development for already well-known proteins (e.g. Ab), ...
These fibrils influence cell behavior by allowing cell attachment to the nano-structured collagen matrix. In addition to these physical cues, ECM also presents various biochemical cues through ECM integrated biomolecules such as proteins (e.g., fibronectin, vitronectin, and laminin), growth factors, ...
Identify the composition of blood plasma, including its most important solutes and plasma proteins. What is the cell from which all blood cells originate? Identify the term: A type of lymphocyte that differentiates into a plasma cell. What is the most abundant buffer in plasma and i...
2g). Since neither the network nor starch granules inside the matrix are present in wild-type Chlamydomonas cells, we favour the view that both features are aberrant consequences of SAGA1 expression in the absence of other relevant Chlamydomonas proteins. In the CrRBCS2;EPYC1-GFP;SAGA1-mCherry...
Like the horse of Troy, scientists have developed a way to sneak synthetic cells right into tumor tissue, where they then begin producing cancer-fighting proteins from the inside. The technique was tested in both cell cultures and in mice, and found to b
Moreover, proteins and amino acids can be first degraded to pyruvic acid via bacterial metabolism and then fermented into hydrogen. Many studies on different pretreatment methods of EC have been conducted, and the fermentation of pretreated EC biomass to produce hydrogen has also been investigated. ...
The proC overexpression and adc1 knockout in Synechocystis apparently induced the changes in proline and glutamate contents inside the cells, which partially alleviated cells under nitrogen and phosphorus deprivation. However, the acetate addition, enhancing acetyl-CoA metabolite, significantly boosted the...
Magnetic nanoparticles—called magnetosomes—inside the cells are organized in a chain-like fashion, thus creating an intracellular compass needle. Every magnetosome includes a magnetic iron oxide core that is enclosed by a membrane. This membrane includes a range of different proteins, apart from ...