Following intramuscular administration of prochlorperazine edisylate, the drug has an onset of action within ten to twenty minutes and a duration of action of three to four hours. Indications and Usage for Prochlorperazine To control severe nausea and vomiting. For the treatment of schizophrenia. ...
Consider providing an antiemetic drug. These agents may be given IV, intramuscularly (IM), PO, or PR. They fall into four distinct classes. SeeTable 22.1 for a list of common antiemetic agents. View chapter on ClinicalKey Prochlorperazine Claire Davis, in xPharm: The Comprehensive Pharmac...
Within 60 minutes after injection, 74% (31/42) of those who received prochlorperazine had complete relief; 14% (6/42) of the patients had partial relief. Overall, there was complete or partial relief of pain in 88% (37/42) of the drug group and in 45% (18/40) of the placebo ...
Participants: Seventy consenting adults from a convenience sample of patients presenting with migraine headache similar to that experienced in at least one prior episode. Exclusion criteria were pregnancy, fever, signs of meningismus, altered sensorium, drug or alcohol use, oxygen saturation less than...
Eighteen of the 37 patients achieved a complete or partial elimination of symptoms: seven with nabilone alone, three with prochlorperazine alone, and eight with each drug. Nabilone appeared to be the more effective antiemetic for patients who received chemotherapy agents other than high dose DDP...
The US Food and Drug Administration (FDA) has approved the use of first-generation antipsychotic drugs are used to treat the causes of death in elderly patients with dementia [1]. The FDA issued a warning in 2005 concerning using antipsychotics for behavioral and psychological symptoms of dementia...
Intracellular perfusion with PCP did not substitute for the extracellularly applied drug, indicating that its binding sites are accessible from the extracellular space. Since P2X7 current potentiation by PCP was voltage-dependent, at least one site may be located within the electrical field of the ...