The final section of this chapter discusses the use of various computational modeling strategies that could facilitate the design and scale-up of manufacturing processes.Karol M. cki, *John JosephKjell O. ErikssonBiopharmaceutical Processing
There is an extensive work about the control of wet granulation processes and the scale-up methodologies in the literature.1-3 Scale-up methodologies can be classified into 2 main categories4: (a) methods based on engineering principles that apply fixed mathematical rules to process parameters and...
Scaling Lean : Principles Over Process Large and Mid-size organizations today are trying to act like startups. Theyoutsource software developmentto implement lean methodology in their curriculum or trying to implement with their development teams. Lean methodology is not something new which enables sc...
Scale-up theory for the micronizer-type jet mill was developed analytically, by combining comminution kinetics and classification principles with closed-circuit grinding system theory. Geometrical similarities in relation to mill diamete... Tanaka,T. - 《Industrial & Engineering Chemistry Process Design ...
Freeze drying - Principles and practice for successful scale-up to manufacturing Freeze Drying involves transfer of heat and mass to and from the product under preparation, respectively, thus it is necessary to scale these transport phe... SC Tsinontides,P Rajniak,D Pham,... - 《International...
By applying lean principles, organizations can streamline their processes, reduce lead times, and improve overall efficiency. Lean techniques, such as value stream mapping, 5S, and Just-in-Time (JIT) production, help to identify and eliminate non-value-added activities, optimize flow, and create...
A scale-up method for a metallurgical process, belonging to the field of metallurgy and chemical industry equipment research and scale up. Said method comprises: using a metallurgical macroscopic reaction kinetics research method to determine an overall rate equation and determine the most critical proc...
including process design principles, to enable the reader to rationalize the set-up of a bioseparation process. The second part illustrates by way of case studies and sample protocols how the theory learned in the first part may be applied to real-life problems. Chapters look at: Downstream Pr...
The division between constructors and mappings gives us general induction principles. If a sort D is declared with a number of constructors, then we may assume that every term of sort D can be written as the application of a constructor to a number of arguments chosen from the respective ar...
(MVPs), and iterating based on customer feedback. By adopting lean startup principles, organizations can reduce the risk of failure, validate market demand, and accelerate time-to-market for innovative offerings.Consider Lean Startup when launching new products or ventures, especially in uncertain...