This work shows not only that it can happen by two different processes, but how drugs can be developed to activate this newly discovered second cell-killing process in a much smarter, more effective way. We are at an early stage with this work but it could represent a new way of ...
Of particular utility is the separation of cells from peripheral blood mononuclear cells, where members of the lymphoid or myeloid lineages may be isolated and used for research, diagnosis or therapy. Also of interest are cellular separation from bone marrow, tumor suspensions or lymphoid tissue ...
In addition, the growth in commercially viable cell therapeutic products has been hampered because of a lack of manufacturing platforms flexible enough to accommodate multiple therapeutic processes. New automated manufacturing platforms are emerging to address the current deficiencies in the cell therapy ...
A medical oncologist discusses the referral process for patients being considered for CAR T-cell therapy in early relapsed/refractory multiple myeloma, highlighting factors that inform treatment selection.This is a modal window. This video is either unavailable or not supported in this browser E...
The FDA approved a new manufacturing process that will shorten the median turnaround time (TAT) of axicabtagene ciloleucel(Yescarta; Kite) from 16 days to 14 days. Reducing the time it takes to manufacture this chimeric antigen receptor T (CAR T)-cell therapy can speed ...
Mesenchymal stem cells (MSCs) and pluripotent stem cells (PSCs) emerge as promising tools for tissue engineering, cell therapy, and drug screening. Their potential use in clinical applications requires the efficient production of differentiated cells at large scale. Glucose, amino acid, and oxygen ...
:a prominent or projecting part of an organism or organic structure a boneprocess a nerve cellprocess Legal Definition process noun pro·cessˈprä-ˌses, ˈprō- 1 :a continuous operation, art, or method especially in manufacture ...
The changes of cell factors in patients with severe hepatitis complicated with hypoxemia before and after the intravenous infussion of oxygenenriched liquids Objective Seeking for a new therapy for effectively correc ting hypoxemia of severe hepatitis cases in terms of oxygen-enriched liquids in f usio...
“We are excited to launch this world-class Closed Process CAR-T Cell Therapy Platform, which will enhance the integrated support we provide for our customers,” said Felix Hsu, Senior Vice President and Global Head of WuXi AppTec Advanced Therapies. “We are hopeful that this new platform wi...
Activity of Nitrogen-Containing and Non-Nitrogen-Containing Bisphosphonates on Tumor Cell Lines However, on esterification, this IC50 value drops to 6.8 µM, Table 1, a factor of ∼20× improvement in potency due to masking of the highly ... Yonghui,Zhang,Annette,... - 《Journal of ...