PROCAM risk scoreOxidative stress and paraoxonase activity play a significant role in the pathogenesis of cardiovascular disease (CVD). The Prospective Cardiovascular M眉nster (PROCAM) study evaluated the prevalence of CVD risk factors and postulated the prediction of future CVD events. We therefore ...
Design and methods Oxidative stress status parameters [lipid peroxidation measured as thiobarbituric acid-reacting substances (TBARS), superoxide anion (O2−), superoxide dismutase (SOD) activity, total sulphydryl group content] and paraoxonase (PON1) status were assessed in 211 participants. The ...
An NPHS-II risk algorithm, developed using a 50% random subset, and including age, triglyceride, total cholesterol, smoking status, and systolic blood pressure at recruitment, gave an ROC of 0.64 (0.58–0.70) with a DR5 of 10.7% when applied to the second half of the data. Adding family...