Ajmaline versus procainamide challenge test in the diagnosis of sudden unexplained death or Brugada syndromedoi:10.1016/S0735-1097(02)80491-0GumpanartVeerakulandLertlakChaothaweeandBanharnKoanantakulandKoonlaweeSDOSJournal of the American College of Cardiology...
No subjects with a negative procainamide challenge were subsequently diagnosed with Brugada syndrome. Genetic testing was conducted in 10 of the 12 subjects with a provoked Brugada pattern and was positive for a mutation in the SCN5A gene in 1. Conclusion Irrespective of the baseline ECG, ...
In 166, baseline EPS was negative and class I drug challenge was performed (90 procainamide, 76 flecainide). The final value and percentage increase in the His-ventricular interval (76 ± 16 ms vs. 64 ± 10 ms and 22.5 ± 6.2% vs. 11.8 ± 5.3%; p < 0.001) and diagnostic yield (...