Molecular diagnosis of inherited disorders: lessons from hemoglobinopathies. Hemoglobinopathies constitute a major health problem worldwide, with a high carrier frequency, particularly in certain regions where malaria has been endem... GP Patrinos,P Kollia,MN Papadakis - 《Human Mutation》 被引量:...
The viscosity of highly and densely polymerized human hemoglobin is low enough in reasonable concentrations to serve as an effective oxygen carrying blood substitute. But polymerisation with glutardialdehyde leads to instable polymers. In contrast polymerisation with diisocyanate gives stable polymers which...
38,39 Six biomarkers were used: overweight, high blood pressure, elevated total cholesterol level, low high-density cholesterol level, elevated glycosylated hemoglobin level, and low maximum oxygen consumption. Study members were clustered if they had at least 3 risk factors.40 High-Sensitivity C-...
The gender difference in “normal” hemoglobin levels and iron reserves is affected by menstruation and endocrinological variances, including testosterone.6 With any variation in menstruation, those differences become more apparent; however, with the normalization of HMB, the problem is compounded.7 This...
Hemoglobin S variants in blood donors of the Hematology and Hemotherapy Center of the state of Piauí (Hemopi): understanding the epidemiological profile t... The most highly prevalent inherited disease in Brazil and in the world, sickle cell anemia, is considered a public health problem. Charact...
Internal exposure to heat-induced food contaminants in omnivores, vegans and strict raw food eaters: biomarkers of exposure to acrylamide (hemoglobin adducts, urinary mercapturic acids) and new insights on its endogenous formation 2024, Archives of Toxicology Human Intervention Study: Alkylresorcinol Metabo...
Major depressive disorder (MDD) is an incapacitating condition characterized by loss of interest, anhedonia and low mood, which affects almost 4% of people worldwide. With rising prevalence, it is considered a public health issue that affects economic productivity and heavily increases health costs...
We used a NIRScout 8–16 (NIRx Medizintechnik GmbH, Germany) Optical Topography system to record oxy-hemoglobin (HbO) and deoxy-hemoglobin (HbR) concentration changes for each dyad. The four 2 × 2 probe sets were attached to an EEG cap with 10–20 configuration. The standard electrode locat...
Abbreviations: HBA1c, glycated hemoglobin; PAID, Problem Areas in Diabetes Questionnaire; PHQ-9, Patient Health Questionnaire; M, mean; SD, standard deviation; WHO-5, World Health Organization-Five Well-Being Index. 4436 https://doi.org/10.2147/DMSO.S322850 DovePress Powered by TCPDF (www....
Patients in EVE showed higher serum cholesterol (205 ± 41 vs. 235 ± 41 mg/dL, p = 0.0012) and lower hemoglobin concentration (13.6 ± 1.4 vs. 12.4 ± 1.9, p = 0.01). Renal function was not significantly different in the two groups (3 Y creatinine: TAC 1.4 ± 0.8 vs. EVE 1.6 ...