PROBEProspective, Randomized, Open, Blinded End-Point(clinical trial design) PROBEPersonal Research on Basically Everything(education) PROBEPreternatural Research Bureau(Doctor Who spinoff series) PROBEProject Review and Objective Evaluation(health records; UK) ...
This paper reports on the design of a prototype in-vivo Stokes polarimetry probe for skin lesion evaluation, and preliminary results from skin phantom and clinical trials of this device. The probe releases a single millisecond-long pulse from a laser diode with either linear or circular ...
We propose a cluster randomized trial design using a mass immunization campaign among all age groups, with monitoring over a 4-year period of a variety of outcomes. The primary outcome would be the vaccine preventable disease incidence of prolonged fever hospitalization. Sample size calculations ...
(Fig. 1a), probes hensively fish and identify multiple protein targets of active small derived from the parent molecules are first designed and molecules, and it consists of two key steps: (1) probe design and synthesized based on a structure–activity relationship (SAR) study synthesis and ...
Further information on research design is available in theNature Portfolio Reporting Summarylinked to this article. Data availability The authors declare that all data supporting the findings of this study are available within the paper and its supplementary information files.Source dataare provided with...
These serve as important confounders that should be considered in interpretation of L-carnitine clinical studies and broadly holds lessons for future clinical trial design in sepsis. Consideration of these factors are needed if precision medicine in sepsis is to be achieved.doi:10.1002/phar.2448...
Study design and participants All patients diagnosed with breast cancer, which were candidates for breast conserving surgery between 5 May 2022 to 15 May 2023 registered in the study. In patients with various histologic subtypes of breast tumors, who underwent first-line BCS, the cavity side margin...
In the clinical setting, AAAs are diagnosed by the screening of the abdominal aorta using ultrasound, computed tomography angiography (CTA), or magnetic resonance angiography (MRA). The majority of the identified AAAs are small in size and do not need immediate surgical intervention7,8. However,...
Figure1(c)shows the magnetic characteristics of Resovist33(magnetic fluid containing the SPIONs) measured using the SQUID MPMS-5S, Quantum Design, Inc., US, for various iron amount 140, 280, and 560 μg, corresponding to 5, 10, and 20 μL of Resovist, respectively. Increasing the applied...
A collaborative effort between ZY and HZ led to the design of the project and funding for its implementation. XKM wrote the manuscript, conducted animal studies, imaging, in vitro studies and data analysis. TLL conducted nanobody generation and radiolabelings. XKM, WYZ, YY, JPT, DW and JYZ...