[15], anti-microbial [16], hypocholesterolemic [17], skin photoprotective properties [18], anti-proliferative and pro-apoptotic effect in several cancer cell lines such as MDA-MB-231 [[19], [20], [21]], SkBr3 [22], MCF-7 [22,23], JIMT-1 [24], Caco-2 [25], A375 [26] ...
This toxin demonstrated cytotoxic effect on two different human breast cancer cell lines (MCF-7 and SKBr3) and on PC3 human prostate cancer cells. In particular, agelasine B releases Ca2+ from the endoplasmic reticulum that is correlated to induced DNA fragmentation and apoptosis [74]. This ...