1. PRKCQ〢S1 could promote CRC cell proliferation and migration via miR87/YBX1 axis. 2. PRKCQ〢S1 could promote tumor progression in vivo. 3. The study reveals PRKCQ〢S1/miR87/YBX1 axis for the first time. 4. PRKCQ〢S1 could be regarded as a therapeutic target in CRC treatment.doi:...
Analysis of Immune and Prognostic-Related lncRNA PRKCQ-AS1 for Predicting Prognosis and Regulating Effect in Sepsis Xian Ding, Wenqi Liang, Hongjuan Xia, Yuee Liu, Shuxiong Liu, Xinyu Xia, show all Pages 279-299 | Received 28 Aug 2023, Accepted 07 Dec 2023, Published online: 11 ...
Then we verified the expression of PRKCQ-AS1 in MDS patients and features in SKM-1 cells.Results: Bioinformatics analysis revealed that the DNMT-associated DE-lncRNA PRKCQ-AS1 was functionally related to DNA methylation. The target genes of PRKCQ-AS1 associated with DNA methylation ...
Cell function tests confirmed that PRKCQ-AS1 could inhibit sepsis model cells viability and promote cell apoptosis, inflammatory damage and oxidative stress.Conclusion We constructed immune-related lncRNA-mRNA regulatory networks in the progression of sepsis and confirmed that PRKCQ-AS1 is ...