First example of a Prins-Ritter reaction on terpenoids:a diastereoselective route to novel4-amido-octahydro-2 H-chromenes. Sarmah B,Baishya G,Baruah R.K. RSC Adv . 2014B. Sarmah, G. Baishya, R.K. Baruah, First example of a Prins-Ritter reaction on terpenoids: a diastereoselective route ...
ChemInform Abstract: Iodine/AcCl‐Catalyzed Prins‐Ritter Reaction: Synthesis of 4‐Amido Tetrahydropyrans.pyran derivativesdiastereoselective syntheses, enantioselective syntheses (incl. cis/trans-isomerism)ring closure reactionsHomoallylic alcohols (I), carbonyl compounds (II) or (V) and acetonitrile (III...
This is the first report on the synthesis of hexahydro-1H-furo[3,4-c]pyranyl amide through a sequential Prins/Ritter reactions using B(C6F5)3 as a mild Lewis acid.doi:10.1016/j.tetlet.2014.05.115Reddy, B.V. SubbaGhanty, Supriya
This process is a one-flask tandem Prins–Ritter reaction.228 Later, Willis and coworkers reported the intramolecular Prins–Ritter conversion in equation 136. This reaction was notable for both its excellent yield and high diastereoselectivity. Both the cis- and trans-alkenes yielded the same all...
Prins-Ritter reactioncyclizationspiro cyclic compoundsHomoallylic alcohols, carbonyl compounds and nitriles undergo a smooth tandem Prins-Ritter type cyclization in the presence of iodine/AcCl at room temperature to produce 4-acetamido tetrahydropyrans in high yields with all m-selectivity....
Prins-Ritter amidationring-closing metathesis (RCM)A stereoselective total synthesis of the 2-(2-hydroxyalkyl)piperidine alkaloids has been accomplished by a Prins–Ritter amidation sequence. Other steps involved in this synthesis are Jacobsen's hydrolytic kinetic resolution (HRK) and ring-closing ...
The reaction involves the initial formation of the pyrrolidin-3-ylidenemethylium carbocation via the Prins cyclization reaction followed by the Ritter reaction to produce N-(pyrrolidine-3-ylidenemethyl)acetamides. This methodology is also used for the synthesis of their piperidine derivatives....
Bismuth(III) triflate is found to be an effective Lewis acid in catalyzing a three-component reaction of homoallylic alcohol, carbonyl compound, and nitrile at ambient temperature via the Prins-Ritter sequence to furnish 4-amidotetrahydropyrans in high yields, all with cis selectivity. Spirocyclic...
Triflic acidHomoallylic amines4-Amidopiperidines4-Amidopiperidine derivatives have been prepared for the first time in good yields and with high selectivity by means of aza-Prins-Ritter reaction sequence using 1.2equiv of triflic acid under mild reaction conditions....
ChemInform Abstract: Triflic Acid Promoted Aza-Prins-Ritter Reaction Sequence: A Novel Synthesis of 4-Amidopiperidine Derivatives.pyridine derivativesdiastereoselective syntheses, enantioselective syntheses (incl. cis/trans-isomerism)The protocol yields trans-2,4-disubstituted piperidines (IV) under mild ...