germ cell- a spermatozoon or an ovum; a cell responsible for transmitting DNA to the next generation reproductive cell,sex cell cell- (biology) the basic structural and functional unit of all organisms; they may exist as independent units of life (as in monads) or may form colonies or tissu...
(http://germline.mcdb.ucla.edu). Previously published RNA-seq data of male and female hPGCs and somatic cells25,52,53and single-cell RNA-seq data from female germ cells30and from female FCGs40that were reanalysed here are available under the following accession codes:GSE63392(ref.25),GSE...
Comparison of the MicroRNA Expression Profiles of Male and Female Avian Primordial Germ Cell Lines (2002) Epigenetic reprogramming in mouse primordial germ cells. Mech. Mammalian-specific genomic functions: newly acquired traits generated by genomic imprinting and LTR retrotransposon-derived genes in mamma...
investigations have not only confirmed the leading effect of germ cells on gonadal differentiation and sexual dimorphism, but also found that the complete depletion of primordial germ cells in the all-female polyploid fish leads to sex-biased gene expression alteration and sterile all-male occurrence....
Thus these results demonstrate that B/C-treatment induces an irreversible germ cell depletion and possibly a defect in the process of follicle development that results in subsequent infertility in mice. Table 1 Reproduction activity of female mice at 15th weeks after B/C treatment Full size table ...
Investigations of primordial follicle formation and growth are fundamental to our understanding of female gamete production. In all mammalian females the f... M H.,Picton - 《Theriogenology》 被引量: 268发表: 2001年 Activation of follicle development: the primordial follicle primordial germ cellprimor...
the balance between low or high apoptosis levels is supposed to control oocytes survival and the maturation of a female or a male gonad [26]. While the loss of oocytes in juvenile gonads is part of the normal process of sex differentiation to testis, an early decrease of PGCs during the ...
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A recent study has demonstrated that female human embryonic stem cell (hESCs) can differentiate into VASA-positive human oocyte-like cells7. However, an approach for differentiating male primate PGCLCs into more advanced VASA positive stages is lacking. Advanced differentiation and generation of ...
the inadequate number of oocytes that are acquired from later ovarian follicle stages limits current applications within endangered species conservation breeding programs2. First and foremost, improving female gamete yield is essential in order to progress. Studies involved in optimising these techniques cou...