Previous studies have suggested that the presence of human epididymal protein 4 (HE4) in pleural fluid can be used to diagnose malignant pleural effusion (MPE) with moderate accuracy. However, the factors that affect the diagnostic accuracy of HE4 remain unknown. This study aimed to examine how ...
The release of the therapeutic factors depends on several factors, such as temperature, type of NPs formulation, release medium, and pH [34]. Also, different events lead to the drug release kinetics in PLGA microspheres, including diffusion of the drug through the polymer matrix, polymer degradat...