G72 primate-specific gene: a still enigmatic element in psychiatric disorders. Cell Mol. Life Sci., 73: 2029-2039, 2016.Sacchi S, Binelli G, Pollegioni L. G72 primate-specific gene: a still enigmatic element in psychiatric disorders. Cell Mol Life Sci (2016) 73:2029-39. doi:10.1007/...
Ret finger protein-like 1 (RFPL1) is a primate-specific target gene of Pax6, a key transcription factor for pancreas, eye and neocortex development. However, its cellular activity remains elusive. In this article, we report that Pax6-elicited expression
We hypothesize that higher primate-specific gene evolution may lead to these differences and target genes involved in human preterm birth, an area of global health significance./p pMethods/p pWe performed a comparative genomics screen of highly conserved noncoding elements and identified itPLA2G4C...
Genomic changes specific to higher primates are regarded as primate-specific genomic information (PSI). Using PSI to inform genetic studies is highly desirable but hampered by three factors: heterogeneity among PSI studies, lack of integrated profiles of the identified PSI elements and dearth of rele...
The role of the CYTH4 gene in the pathogenesis of type I BD remains to be clarified in the future studies. 展开 关键词: Bipolar disorder \{CYTH4\} GTTT-repeat Primate-specific DOI: 10.1016/j.pnpbp.2014.09.001 被引量: 17 年份: 2015 ...
Primate-specific endogenous retrovirus-driven transcription defines naive-like stem cellsdoi:10.1038/nature13804Naive embryonic stem cells hold great promise for ... - 《Nature》 被引量: 0发表: 2014年 Robust In Vitro Induction of Human Germ Cell Fate from Pluripotent Stem Cells Mechanisms underlying...
This question is important because a gene that has been positively selected independently in the human and in other primate lineages may be less likely to be involved in human specific phenotypic changes such as dietary habits or cognitive abilities. To answer this question, we analysed heterozygous...
microRNA GeneEntire Human GenomeWhitehead Institute"Finding a group of genes that is specific to primates is very important for understanding our evolution, and bears significant diagnostic and therapeutic potential," lead researcher Isaac Bentwich, at Rosetta Genomics in Rehovot, told The Scientist....
Analysis of these data enabled the discovery of primate-specific gene regulatory elements and the demarcation of the exons of multiple genes. Much of the information content of the comprehensive primate sequence comparisons could be captured with a small subset of phylogenetically close primates. These...
Computer analyses of the 3鈥 -flanking DNA sequence of the human elastase I gene revealed a significant degree of similarity with seven human gene sequences in the CenBank and EMBL databases. Cenomic Southern analysis indicates that the shared nucleotide sequences are a primate-specific family of...