DNA primase is a DNA-dependent RNA polymerase that synthesizes the first ~10 nucleotides and then transfers the substrate to polymerase α to complete primer synthesis. From:Methods in Enzymology,2017 Also in s
De novo initiation of DNA synthesis by DNA polymerases requires formation of an initial "primer" on the template. In eukaryotes, this function is provided by a distinct DNA primase. Primase, a DNA-dependent RNA polymerase, generates short (8-12 nt) RNA primers on ssDNA templates. These ...
DNA replication is heavily dependent on several enzymes to progress. An example of these enzymes is DNA polymerase. DNA polymerase is found in both eukaryotes and prokaryotes and is a highly conserved structure. This means that the active site of this enzyme, which is where it processes the ...
Therefore, it is warranted to better investigate the biological and molecular processes in HCC and provide novel targets for HCC. DNA primases synthesize primers for DNA polymerases-mediated DNA replication. DNA primases are also defined as DNA-dependent RNA polymerases. The polymerases complex ...
noun (biochemistry) An RNA polymerase involved in the initiation of DNA synthesis 更多 primase 的语法和变格 primase ( plural primases) 更多 例句与“ primase " 变形 干 This primase is structurally similar to many viral RNA-dependent RNA polymerases, reverse transcriptases, cyclic nucleotide ...
T7 primase, which can synthesize RNA primers, is located in the N-terminal half of the multifunctional gene 4 helicase-primase protein13. The primase domain is composed of an RNA polymerase domain (RPD) and a zinc-binding domain (ZBD). The two domains are connected by an unstructured ...
DNA polymerase utilizes the RNA primers and adds nucleotides matched to the template strand in the 5′ to 3′ direction4. While the leading strand is replicated continuously to the 3′ end of the complementary strand, the lagging strand in the opposite direction can only synthesize Okazaki ...
Preparing the complexes at various times after the release of cells from a double thymidine block showed the complexes as well as the complex-associated enzyme activities to be cell-cycle dependent. The DNA and RNA polymerase-related activities were highest in late S phase, 7 and 9 h, ...
Equi-phi29 DNA Polymerase(Equi-phi29 DNA聚合酶) Bst 2.0 DNA Polymerase(Bst 2.0 DNA 聚合酶) Bst 3.0 DNA/RNA Polymerase(Bst 3.0 DNA/RNA 聚合酶) Bst 4.0 DNA/RNA Polymerase(Bst 4.0 DNA/RNA 聚合酶) Bsu DNA Polymerase (Bsu DNA 聚合酶) Sau DNA Polymerase(Sau DNA 聚合酶) Klenow Fragment(...
DNA Recognition/Processing | DNA Polymerase Alpha-Primase: Biochemical and Structural Mechanisms The Roles of Pol Prim Subunits in Priming Pol-prim is comprised of two differentpolymerases,primaseand pol α, whose activities are distinct but tightly coordinated. Primase is a DNA dependentRNApolymerasetha...