Elucidating protein-protein interactions (PPIs) is essential to constructing protein interaction networks and facilitating our understanding of the general principles of biological systems. Previous studies have revealed that interacting protein pairs can be predicted by their primary structure. Most of these...
Elucidating protein-protein interactions (PPIs) is essential to constructing protein interaction networks and facilitating our understanding of the general principles of biological systems. Previous studies have revealed that interacting protein pairs can be predicted by their primary structure. Most of these...
we focused on the function of the Kv1.3, Kv1.5 and Kir2.1 potassium channels expressed in both BV2 cells and primary microglia cultures, which may impact the cellular migration process. (2) Methods: Using an immunocytochemical approach, we were able to show the presence of the investigated cha...
Transmission of pain signals from primary sensory neurons to secondary neurons of the central nervous system is critically dependent on presynaptic voltage-gated calcium channels. Calcium channel-binding domain 3 (CBD3), derived from the collapsin response mediator protein 2 (CRMP2), is a peptide ...
Referring to the vector correlation matrix, the structures of the three periodic tables changed over time as a function of standing activity. The correlations to the D0–D1 table decreased from 0.50 (D1–D3) to 0.25 (D3–D7). The compromise was defined with a weighted average of the th...
National Standards Organisations usually monitor both instrument calibration and mechanical testing laboratories. Although each different country has its own structure for the maintenance of standards, each of these different frameworks tends to be equivalent in its effect in ensuring that the requirements ...
This invention relates to the identification, cloning and expression of an auto-antigen which is recognised as a target in the characteristic autoantibody response in primary biliary cirrhosis (PBC), and to the use of this protein, fragments thereof or fused polypeptides containing the protein or fr...
Fibril formation occurs through the primary nucleation and subsequent fibril growth[7] in the solution, in which protein concentration is above the solubility. It is analogous to the crystallization in a supersaturated solution[8], [9]. The supersaturation state is divided into two states in detail...
(encoding for a plasma membrane Ca2+ATPase)15. Mutations were clustered within the M4 helix involved in ion binding, suggesting a gain-of-function mechanism; however, the authors originally described the loss of pump function in mutant ATPases (which may contribute to depolarization). Subsequent ...
But, realization over the full structure range was deemed impossible due to a miscibility gap corresponding to the amber spectral range. In this study, we utilize plasma-assisted molecular beam epitaxy (PAMBE) to fabricate cubic InxGa1-xN films on c-GaN/AlN/3C-SiC/Si template substrates that...