researches which have directed at primary resistance or acquired resistance exclusively are reviewed here.The different mechanisms of primary resistance and acquired resistance of trastuzumab suggest that we should give different clinical therapy strategies to different subgroups of clinical resistance patients....
Editorial: Primary and acquired resistance in lung cancerdoi:10.3389/fonc.2023.1310331LUNG cancerBruno, RossellaSimbolo, MichelePetrini, IacopoFrontiers in Oncology
resulting in significant clinical efficacy and lasting responses. However, these therapies do not work for a large proportion of patients initially, which is called primary resistance. And more frustrating is that most patients eventually develop acquired resistance after ...
(D) Patient has an initial response to immunotherapy but later progressed; true acquired resistance during the immunotherapy. Primary and Adaptive Resistance to Immunotherapy Patients who have primary resistance to checkpoint inhibitors do not respond to the initial therapy. Ongoing studies indicate that ...
EPHA2 Blockade Overcomes Acquired Resistance to EGFR Kinase Inhibitors in Lung Cancer Despite the success of treating EGFR-mutant lung cancer patients with EGFR tyrosine kinase inhibitors (TKI), all patients eventually acquire resistance to these therapies. Although various resistance mechanisms have been...
Real-World Primary Resistance to First-Line Immune-Based Combinations in Patients with Advanced Renal Cell Carcinoma (ARON-1) Abstract Background Therapeutic advancements based on immuno-oncology combinations have revolutionized the management of patients with renal cell carcinoma. However, patients who ...
aTaxanes are a standard first-line option for metastatic breast cancer (MBC), but their utility may be limited by primary or acquired resistance. Taxanes是一个标准最重要的选择为变形的乳腺癌 (MBC),但他们的公共事业也许由主要或获取的抵抗限制。 [translate] ...
The ability of cancer cells to ensure T-cell exclusion from the tumor microenvironment is a significant mechanism of resistance to anti-PD-1/PD-L1 therapy. Evidence indicates crucial roles of Batf3-dependent conventional type-1 dendritic cells (cDC1s) for inducing antitumor T-cell immunity; ...
primary resistance, where patients do not respond to PD-1/PD-L1 blockade initially. Andmore distressingly, most patients eventually develop acquired resistance after an initial response to PD-1/PD-L1blockade. The mechanisms underlying primary and acquired resistance to PD-1/PD-L1 blockade have ...
5.Resistência primária e adquirida à pirazinamida em pacientes com tuberculose pulmonar atendidos em um hospital de referência no Recife Primary and acquired pyrazinamide resistance in patients with pulmonary tuberculosis treated at a referral hospital in the city of Recife, Brazil and spring 机译...