This finding calls into question whether this phenomenon fits the traditional definition of a direct reprogramming, as these skin NC precursors are developmentally derived from the brain, express neural stem cell genes, and have an intrinsic bias to produce neurons under certain culture conditions (...
PK, MD and FH are responsible for the study design, definition of the endpoints and preparation of the protocol. TB is responsible for the statistical analysis plan. AU, IA and RH provided support for the technical aspects of the intervention arms and provided a clinical perspective as experts...
We analysed virally encoded miRNA expression in CD34+(Fig. 1a) and CD14+(Fig. 1b) cells at 4 days post infection (dpi) with TB40 IE86-YFP. Consistent with our previous analyses of experimentally latently infected CD34+cells at this time point of infection2,41, these CD34+cells showed ...
The statistical analysis used in each experiment and the definition of n are stated in the figure legends. Data and Code Availability This study did not generate any unique datasets or code. Acknowledgments We thank J. Barthe for expert assistance and C.C. Hui for Kif7 mutant mice. Work ...
The amount of biomass harvested per unit of area (including used and unused residues, according to our definition of HANPPharv) varied greatly between countries, time periods and land use cate- gories (Fig. 5). The most significant increase in biomass yields took place on cropland (Fig. ...
Our definition of “bulky nodes” included size ≥10 mm, radiological abnormal appearance and/or positivity at PET scan. In all cases of primary surgery, a preoperative CT scan was performed to clearly understand the extension and localization of the disease, while patients with recurrent disease ...