The theory of parathyroid hormone action based upon urinary phosphate excretion is discussed and the following clinical observations are recorded which appear to conflict with it. The symptomatology of rapidly growing (? malignant) tumours of the parathyroid indicates that bone lesions will always occur...
Pathogenesis of hypocalcemia in magnesium depletion: Normal end-organ responsiveness to parathyroid hormone Pathogenesis of hypocalcemia in primary hypomagnesemia: normal end-organ responsiveness to parathyroid hormone, impaired parathyroid gland function. J Clin Invest. 1973 Jan; 52 (1):153–160. [ PMC...
Parallel research identified the 550 kDa glycoprotein megalin, which also is expressed on the parathyroid cell surface, as another potential calcium sensing protein. Although this protein expresses numerous calcium binding sites on its external domain, its main function may be calcium sensitive binding ...
Parathyroid hormone-related protein production by primary cultures of mammary epithelial cells. J Cell Physiol 1992;150:304-311.Ferrari SL , Rizzoli R , Bonjour JP . 1992 . Parathyroid hormone-related protein production by primary cultures of mammary epithelial cells . J Cell Physiol 150 : 304 ...
Patients with secondary hyperparathyroidism usually have low-normal calcium and elevated parathyroid hormone. The serum phosphorus level may vary based on the etiology, trending towards higher values with reduced kidney function and lower values with vitamin D deficiency. Ultrasonography may reveal thyroid ...
Objective Chondrocytes have been shown to express β1-containing integrins bothin vitro and in situ, but their role in regulating chondrocyte function is poorly understood. The objective of this study was to determine how the relative expression of different integrins may be modulated in relation to...
摘要: A patient with hypercalcaemia had persistently suppressed serum intact parathyroid hormone levels (measured by immunochemiluminometric assay). However, other biochemical tests and open-neck exploration confirmed a diagnosis of primary hyperparathyroidism.关键词:...
Surgical removal of the parathyroid adenoma is recommended in the case of primary hyperparaÂthyroidism complicated by osteoporosis, hyper-calciuria, nephrolithiasis, or impaired renal function. Here we present the case of a 68-year-old man with spontaneous remission of primary hyperparathyroidism...
Recent studies by Anast et al (Science 117-606 1972) and by Sun et al (J.Clin.Invest. 52-153 1973) have shown that severe magnesium deficiency induces inpired parathyroid function and that this impairment is responsible at least in part for the secondary
Evaluate liver enzymes, creatinine, and thyroid function at baseline and periodically during treatment. For patients with TNBC treated with KEYTRUDA in the neoadjuvant setting, monitor blood cortisol at baseline, prior to surgery, and as...