The amino acid sequences of two subunits (80K and 30K) of calcium-activated neutral protease (CANP) were examined to clarify the structure-function relationship of CANP. The 80K subunit is composed of four clear domains (I鈥揑V from the N-terminus). Domain II is a cysteine proteinase ...
Parathyroid hormone and calcitonin regulation of renal function. The physiological significance of parathyroid hormone in the regulation of bone resorption and serum calcium was established by the work of Collip [1] and ... GD Aurbach,DA Heath - 《Kidney International》 被引量: 130发表: 1974年 ...
SMLM has been used alone, in combination or in parallel with other SR approaches, and with EM in a multitude of studies to further our understanding of the function of the primary cilium. For example, SMT has been used to map the diffusion of G protein-coupled receptors (GPCRs) in the...
Main function The main function of the thymus is to act as the site of T-cell differentiation and maturation (from the bone marrow , progenitor cells go to the thymus ). General structure With dense connective tissue capsule Divided into 2 asymmetrical lobes (right is larger): Each lobe ...
The way in which the absolute value of the free energy of a crystal varies with temperature is shown in Figure 3.9b, where H and –TS are plotted as a function of temperature. At the transformation temperature, Tt, the change in heat content ΔH is equal to the latent heat L, while ...
et al. The spectrum of subclinical primary aldosteronism and incident hypertension: a cohort study. Ann. Intern. Med. 167, 630–641 (2017). PubMed PubMed Central Google Scholar Brown, J. M. et al. Aldosterone dysregulation with aging predicts renal vascular function and cardiovascular risk. ...
Recent technological developments are rapidly advancing our understanding of the complex mechanisms that control biogenesis and function of primary cilia across a range of cell types and are starting to tackle this diversity. Here, we examine the structural and functional diversity of primary cilia, ...
The contents of nutritional and functional components of walnut kernel pellicle were analyzed preliminarily by using conventional and instrumental analytical methods.Results showed that the contents of protein,carbohydrates,fat,vitamin B1,vitamin B2,and minerals such as phosphorus,zinc and calcium are 11.03...
Primary cell cultureis defined as theex vivoculture of cells freshly obtained from a tissue. The main advantages of primary cells are their faithfultranscriptomicandproteomicprofile and closer proximity to physiological function and response. Some drawbacks are their requirements for specific substrates and...
30, 31, 32, 33, 34, 35 Gain of function of IDH1 and IDH2 mutation on R132 and R172 two hotpot codons was observed in 10%–28% of ICC cases.32 Fusions, amplifications, translocations, and rearrangements of FGFR genes are found in ICC and are closely related to the initiation and ...