32% and 22% of ivosidenib-treated patients were progression free at 6 months and 12 months respectively, while all patients receiving the placebo had disease progression at data cutoff. The risk of disease progression or death was reduced by 63% with AG120 in ClarIDHy.144 Overall, ivosidenib...
Secondary Outcomes for Safety With Effect Estimates and 95% Confidence Intervals eTable 7. Clinical Events eFigure 1. Graphical Layout of the Study Protocol eFigure 2. Clinical Case Examples eFigure 3. Plot of Troponin T AUC Supplement 4. Data Sharing Statement 1. GBD 2017 DALYs and HALE Col...
Parametric regression models were fitted to interval-censored data. Endpoints: Primary endpoint (time to proteinuria/serum-albumin response; left panel), secondary endpoint (time to permanent eGFR decline; right panel). Abbreviations: eGFR, estimated glomerular filtration rate; inclusion year, year of ...
Safety of Avacopan in ANCA-Associated Vasculitis: Combined Data from Three Clinical Trials. In: ACR Meet Abstr [Internet]. Philadelphia, PA; 2022. Available from: https://acrabstracts.org/abstract/safety-of-avacopan-in-anca-associated-vasculitis-combined-data-from-three-clinical-trials/. van ...
By accepting optional cookies, you consent to the processing of your personal data - including transfers to third parties. Some third parties are outside of the European Economic Area, with varying standards of data protection. See our privacy policy for more information on the use of your perso...
By accepting optional cookies, you consent to the processing of your personal data - including transfers to third parties. Some third parties are outside of the European Economic Area, with varying standards of data protection. See our privacy policy for more information on the use of your perso...
By accepting optional cookies, you consent to the processing of your personal data - including transfers to third parties. Some third parties are outside of the European Economic Area, with varying standards of data protection. See our privacy policy for more information on the use of your perso...
To determine whether ciliary WNT signaling has an impact on LUHMES neuron differentiation, we used a pathway inhibitor (Wnt-C59) [53]. After controlling that Wnt-C59 treatment did not cause any difference in ciliation percentage (data not shown), we examined its impact on the two different ph...
and parents filled out self-report questionnaires. Detailed information on data collection and the composition of the sample can be found in the THINK 1–4 manual (Baudson et al.,2016). Since the analyses of this study represent secondary analyses of the data, approval by the University of Tr...
Of these, 27 were excluded: 16 (4.2%) did not undergo TURB (13 withdrew from the study, 2 had tumor fulguration, and 1 died before surgery), ten (2.6%) had missing or incorrect data, and one (0.3%) had a nondiagnostic histology. Of the remaining 357 participants who were included ...