Background: Primary cutaneous diffuse large B cell lymphoma-leg type (DLBCL-LT) is relatively uncommon lymphoma accounting for about 1 to 3 % of all cutaneous lymphoma and about 10-20% of primary cutaneous B cell lymphomas. There is data for survival outcomes in primary cutaneous B cell ...
All the results led to the diagnosis of a primary cutaneous diffuse large B-cell lymphoma, leg type (PCDLBCL-LT). The following total body was computed tomography (CT)-scan performed reported no other lesions. The patient was treated with systemic corticosteroids (deltacortene 40 mg die) for...
leg typelenalidomideprimary cutaneous diffuse large B‐cell lymphomaKey Clinical Message The primary cutaneous diffuse large B‐cell lymphoma, leg type (PCDLBCL‐LT) has a poor prognosis. R‐CHOP with or without radiotherapy is the available recommendations for first‐line treatment. Relapses/...
Primary cutaneous diffuse large B-cell lymphoma, leg type: case report The report describes the clinic of an aggressive non-Hodgkin lymphoma, primary cutaneous diffuse large-B cell lymphoma, leg type (PCDLBCL-LT), and shows its relevance for addressing the case of a rare lymphoma, with complex...
The term “primary cutaneous large B-cell lymphoma of the leg” (PCLBCL-leg) was used.2,8 In the European Organization for Research and Treatment of Cancer (EORTC) classification for primary cutaneous lymphomas,2 these PCLBCLs-leg were classified as a separate clinical entity of intermediate ...
Objectives To investigate 28 cases of primary cutaneous B-cell lymphoma, including the subtypes PCFCL (n = 10), PCMZL (n = 10) and DLBCL-LT (n = 8) for the number and density of PD-1-positive cells. Methods Immunohistochemical staining and a computerized morphometric analysis for ...
Primary cutaneous B-cell lymphomas are divided into 4 subtypes: primary cutaneous follicular center lymphoma (PC-FCL), primary cutaneous diffuse large B-cell lymphoma leg type (PC-DLBCL-leg type), primary cutaneous marginal zone lymphoma (PC-MZL), and Epstein–Barr positive mucocutaneous ulcers (...
Besides PCNSL, other extranodal DLBCLs with an ABC-like gene expression phenotype also have a high frequency of CD79B and MYD88 L265P mutations, including primary testicular DLBCL, primary breast DLBCL, and primary cutaneous DLBCL, suggesting that these cancers might also respond frequently to ...
Several types of B-cell lymphomas, including both primary cutaneous lymphomas and systemic lymphomas, may affect the skin, with partially overlapping clinical, morphological and immunohistochemical features. Currently, the World Health Organization (WHO)
DLBCL-leg typeprimary cutaneous lymphomacasePrimary cutaneous diffuse large B-cell lymphoma, leg type (PCDLBL-LT) constitutes 1% of all cutaneous lymphomas and it has an aggressive behaviour with poor outcome. PCDLBL-LT is predominantly seen in elderly people, has a female preponderance, and 70%...