Bone Marrow CellsPlasma CellsSpleen淀粉样变骨髓细胞浆细胞脾A 53-year-old man was diagnosed as primary amyloidosis by biopsy specimens of the mucosa in rectum, spleen and bone marrow (BM). BM examination showed 5.5% of plasma cells with some dysplasia. Immunoglobulin heavy chain gene rearrangement...
Bone marrow (BM) cells from lipopol... Shin-Ichi,Nishikawa,Tatsuo,... - 《European Journal of Immunology》 被引量: 18发表: 1985年 Mononuclear cells are not involved in BGP synthesis and secretion Osteocalcin or bone GLA protein (BGP) is found at high levels in only two tissues, the ...
Cell cycle analysis showed that pioglitazone decreased the ratio of G2/M phase in HL60 cells, suggesting the inhibition of cell division. By Western blotting, PPAR-γ protein level was similar in all leukemic cells and normal bone marrow mononuclear cells. Taken together, pioglitazone effectively ...
Second, we identified 28 enhancers that overlap open chromatin in primary CD4+ T cells and were previously paired to a gene in a functional E2G mapping study in the K562 cell line (leukemia bone marrow-isolated lymphoblast cells) [49] (see “Materials and methods”); we refer to these ...
The survival and proliferation of human myeloma cells are considered to be heavily dependent on the microenvironment of bone marrow (BM). This study confirmed that galectin-1 (Gal-1) and SDF-1α were produced by bone marrow mononuclear cells of myeloma patients. The addition of Gal-1 and SDF...
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Bone marrow mononuclear cells (0.4-5.1 × 10(10) cells in total) were administered into the ischaemic limbs. We evaluated short-term safety and efficacy by means of a pain scale, (99m)Tc-tetrofosmin scintigraphy and transcutaneous oxygen tension (TcPO2) before and 4 weeks after treatment. ...
Human bone marrow contains mesenchymal progenitors (mesenchymal stem cells, MSCs). MSCs produce adventitial cells in the human bone marrow microenvironment. MSCs are multipotent stem cells that can differentiate into a variety of cell types, including: osteoblasts (bone cells), chondrocytes (cartilage ...
leukemia but was killed on day 41 due to graft-versus-host disease, whereas one relapsed on day 28 and was found dead on day 32 (Extended Data Fig.7e). Upon termination, no leukemic cells were detected in the bone marrow (BM) of the two surviving TCRFLT3D/Ycell-treated mice (...
Primary myelofibrosis (PMF) is a myeloproliferative neoplasm (MPN) characterized by clonal myeloproliferation, progressive bone marrow (BM) fibrosis, splenomegaly, and anemia. BM fibrosis was previously thought to be a reactive phenomenon induced by mesenchymal stromal cells that are stimulated by the ...