Primary biliary cholangitis (PBC), formerly known as primary biliary cirrhosis, is a chronic disease of the liver, presumably autoimmune in nature, that leads to progressive cholestasis through intrahepatic bile duct destruction [1] and often end-stage liver disease (see the image below). The name...
Primary biliary cholangitis(PBC) is a chronic autoimmune disease of the liver that is characterized by progressive cholestasis and inflammation due to destruction of the intrahepatic bile ducts. If left untreated, it can lead tocirrhosis and liver failure.PBCis thought to be the result of a combin...
at the outset the symptoms may be vague and not attributed to the biliary tree until the liver is significantly affected thereby leading to symptoms such as jaundice
If an endoscopic approach is unsuccessful, biliary dilation and stenting at percutaneous cholangiography can be considered; and Patients with dominant strictures from PSC refractory to endoscopic or percutaneous management should be considered for surgical treatment if concurrent cirrhosis is not present. Liv...