Primary biliary cholangitis (PBC), formerly known as primary biliary cirrhosis, is a chronic disease of the liver, presumably autoimmune in nature, that leads to progressive cholestasis through intrahepatic bile duct destruction [1] and often end-stage liver disease (see the image below). The name...
Critical Relevance Statement Characteristic CT and MR imaging manifestations of primary biliary cholangitis may reflect the course of the disease and provide information associated with histological grading and altered cellular function. Key points Imaging has become highly useful for differentiating PBC from...
原发性胆汁性胆管炎(primary biliary cholangitis,PBC)以前称为原发性胆汁性肝硬化(primary biliary cirrhosis,PBC),是一种以肝内小胆管损伤和胆汁淤积为特点的自身免疫性肝病,其病变由自身免疫异常引起,最终可能进展为肝硬化和肝衰竭,该病具有遗传倾向。本文主要的参考文献为中华医学会肝病学分会《2021原发性胆汁性...
原发性胆汁性胆管炎(primary biliary cholangitis, PBC) 前言:原发性胆汁性胆管炎(primary biliary cholangitis,PBC)以前称为原发性胆汁性肝硬化(primary biliary cirrhosis,PBC),是一种以肝内小胆管损伤和胆汁淤积为特点的自身免疫性肝病,其...
Primary biliary cholangitis (PBC), formally known as primary biliary cirrhosis, is a chronic cholestatic liver disease that predominantly affects adult women of all ages, more commonly in the middle years of life. It presents as a chronic nonsuppurative destructive cholangitis with granuloma formation...
网络原发性胆汁性胆管炎 网络释义 1. 原发性胆汁性胆管炎 ...ry Biliary Cirrhosis)应改名为原发性胆汁性胆管炎(Primary Biliary Cholangitis),两者的缩写都是PBC。 blog.sina.com.cn|基于 1 个网页
A 74-year-old Japanese woman was diagnosed as primary biliary cholangitis (PBC) in her 40’s by using blood tests. Imaging studies, including abdominal ultrasonography (US) and computed tomography (CT), and tumor markers consisting of alpha fetoprotein (AFP) and protein induced by vitamin K ab...
Primary biliary cholangitis (PBC) is an autoimmune liver disease characterized by biliary destruction, progressive cholestasis, and potentially liver cirrhosis. Patients develop a well-orchestrated immune reaction, both innate and adaptive, against mitochondrial antigens that specifically targets intrahepatic bi...
Similar to other autoimmune diseases, primary biliary cholangitis occurs in genetically predisposed individuals upon exposure to environmental triggers, specifically xenobiotics, smoking, and the gut microbiome. Notably, the diversity of the intestinal microbiome is diminished in individuals with primary ...
Primary biliary cholangitis (PBC) is an autoimmune liver disease. The aetiology of PBC remains unclear, and its pathogenesis is complex. Animal models are essential to clarify the pathogenesis of PBC and explore the occurrence of early events. Herein, we