A literature search of past clinical cases with adrenal insufficiency (AI) in the setting of APS and SLE was conducted using major electronic databases. Our aim was to retrieve information about the pathophysiology, diagnosis, and management of similar conditions....
Primary ovarian insufficiency associated with autosomal abnormalities: from chromosome to genome-wide and beyond Objective: The pathophysiology of primary ovarian insufficiency (POI) is not well elucidated. Many candidate genetic aberrations are on the X-chromosome; o... P Vichinsartvichai - 《Menopause...
E. Pathophysiology of bilateral hyperaldosteronism. Curr. Opin. Endocrinol. Diabetes Obes. 29, 233–242 (2022). CAS PubMed Google Scholar Hacini, I. et al. Somatic mutations in adrenals from patients with primary aldosteronism not cured after adrenalectomy suggest common pathogenic mechanisms ...
Both patients and family members are at risk for other autoimmune disorders, including primary adrenal insufficiency (Addison disease), autoimmune thyroid disorders (Graves’ disease, Hashimoto thyroiditis), type 1 diabetes mellitus, pernicious anemia (vitamin B12 deficiency), celiac sprue (often with vi...
the pathophysiology of human hypertension as well as the clinical implications of studies conducted in experimental animal models of hypertension will be addressed. Many organizations including the leading United States authority on blood pressure - the Joint National Committee on the Prevention, Detection...
the pathophysiology of human hypertension as well as the clinical implications of studies conducted in experimental animal models of hypertension will be addressed. Many organizations including the leading United States authority on blood pressure - the Joint National Committee on the Prevention, Detection...
Beyond the mouse models discussed in this review, future animal models replicating the gain-of-function mechanisms implicated in human FH would be interesting tools to study the physiology and pathophysiology of these genes in the adrenal gland. The translation of the genetic findings from the last...
Mutation of the ALADIN 12q13 gene is a commonly reported cause of achalasia in children. It leads to the development of Allgrove syndrome, also known as Triple-A syndrome, which is an autosomal disease characterized by adrenocorticotropin hormone (ACTH) resistant adrenal insufficiency, achalasia, ...
Beyond the mouse models discussed in this review, future animal models replicating the gain-of-function mechanisms implicated in human FH would be interesting tools to study the physiology and pathophysiology of these genes in the adrenal gland. The translation of the genetic findings from the last...
7 Christian Doppler Laboratory for Immunomodulation and Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna 1090, Austria. 8 Department of Immunology, Erasmus MC, University Medical Center, Rotterdam 3015GE, The Netherlands. 9 Department ...