(capsules, powder) daily for 4 weeks. Some patients may need 4 additional weeks of therapy. ➣ To reduce risk of duodenal ulcers caused by Helicobacter pylori Adults: 40 mg P.O. (capsules) daily in morning, given with clarithromycin t.i.d. for 2 weeks; then 20 mg daily for 2 ...
A 28-day toxicity study with a 14-day recovery phase was conducted in juvenile rats with esomeprazole magnesium at doses of 70 to 280 mg/kg/day (about 17 to 68 times a daily oral human dose of 40 mg esomeprazole or 40 mg omeprazole on a body surface area basis). An increase in the...
Dose 15mg once a day for 4 weeks for short-term treatment; 15mg once daily for maintenance. 2 times daily for 10 days; once a day for 18 days if ulcer is present. Pregnancy Category B (USA): Animal studies have shown no effects on fertility or fetotoxicity; however, no studies exist...
A number of clinical trials have found that 20 mg of omeprazole (the over-the-counter strength) each day for 14 days can reduce the symptoms of heartburn. For example, two randomized placebo-controlled trials (with 331 and 320 patients) found that over-the-counter omeprazole significantly redu...
(equivalent to 20 mg omeprazole) Purpose Acid reducer Use treats frequent heartburn (occurs 2 or more days a week) not intended for immediate relief of heartburn; this drug may take 1 to 4 days for...
Daily long-term use (e.g., longer than 3 years) may lead to malabsorption or a deficiency of cyanocobalamin Acute interstitial nephritis has been observed in patients taking PPIs Relief of symptoms does not eliminate the possibility of a gastric malignancy Therapy increases risk of Salmonella, Cam...