We quantify the changes in efficiency of association parameters when incident cases are supplemented with, or replaced by, prevalent cases in simulations. We illustrate our methods by estimating associations of single nucleotide polymorphisms (SNPs) with breast cancer incidence in a sample of controls,...
The HFpEF was the most frequent phenotype in prevalent cases (61.1%) and incident cases (73.9%). Patients with HFrEF had a higher prevalence of coronary heart disease (p = 0.008) and PAD (p = 0.028), and no statistically significant differences was observed in the therapeutic groups...
Hu et al.33 trained a deep learning model to evaluate the retinal age gap as one predictive marker for incident Parkinson’s Disease using fundus images from the UK Biobank, showcasing statistical significance and predictive AUC of 0.71. Nunes et al.34 used optical coherence tomography data to...
Better risk prediction and new molecular targets are key priorities in type 2 diabetes (T2D) research. Little is known about the role of the urine metabolome in predicting the risk of T2D. We aimed to use non-targeted urine metabolomics to discover bioma
MSM status is also a risk factor for incident syphilis infection, which is consistent with the literature [36,39]. In China MSM accounted for 0.3% of the total reported HIV/AIDS cases in 2006. This figure rapidly increased to 13.0% in 2011 [7]. A large number of MSM engage in ...
Since HIV infection was independently associated with prevalent and incident STI, prenatal screening guidelines may need to incorporate HIV status as a high-risk group for repeat testing. 1. Introduction More than 2 million cases of sexually transmitted infections (STI) in the United States were ...
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Apart from modeling potential safety threats based on environmental variables, we see great potential to further improve such models with additional data on crash locations [45], near-miss data [46] and derived incident rates [36]. Yet, these data sources have not been fully exploited due to ...
摘要: Summary table 1 outlines a convenient, though arbitrary, nomenclature for effect size. This terminology will be used throughout the document (including the executivesummary) and the words will consistently be highlighted using bold italics to avoidmisinterpretation.被引量: 19 年份: 2005 ...
When considered alone, these 62 women with incident knee OA had lower serum POSTN levels that the other subjects although the difference did not reach statistical significance after adjustment for age (P = 0.089). When baseline POSTN levels were categorized in quartiles, there was a significant ...