computational screeningdrug-drug cocrystalshot melt extrusionibrutiniboral bioavailability enhancementsolubility enhancementIbrutinib (IBR) is a biopharmaceutical classification system (BCS) class II drug and an irreversible Bruton's tyrosine kinase (BTK) inhibitor. IBR has an extremely low oral bioavailability...
CONSORT Diagram of Screening, Enrollment, and Follow-up of Trial Participants View LargeDownload AD indicates advance directive; and PREPARE, PREPARE For Your Care. aConcerns about privacy of medical information or distrust of the clinic or hospital. bPatient willing to participate, but logistical ...
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In addition, the precision and success rate of ELI-TriScope are also substantially improved. In this study, we prepared 40 vitrified cryo-grids, and 21 of them showed good quality (proper ice thickness and well-distributed fluorescent signals) in the cryo-FM screening and were used for ELI-...
As the sustained and devastating extent of the coronavirus disease 2019 (COVID-19) pandemic becomes apparent, a key focus of public scrutiny in the UK has
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Guidelines for screening and management of late and long-term conse- quences of myeloma and its treatment. Br J Haematol. 2017;176(6):888–907. 9. Gozzetti A, Candi V, Papini G, Bocchia M. Therapeutic advancements in mul- tiple myeloma. Front Oncol. 2014;4:241. 10. Wang XS, Shi...
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AgNAs@m-SiO2-based SERS substrates provide a versatile platform for in situ water quality screening. Its performance in high ionic strength seawater in particular demonstrates its suitability for marine pollution monitoring—a challenging environment where most colloidal SERS substrates fail. 4. ...